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    Glossary Keratin Intermediate Filaments

    structural proteins in cells providing support and resilience

    Keratin Intermediate Filaments (KIFs) are structural proteins found in epithelial cells, including those in the skin, hair, and nails. They provide mechanical support and resilience, helping cells withstand stress and maintain their shape. KIFs are a type of intermediate filament, which are part of the cytoskeleton, a network that supports cell structure and function.

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    1. Expression patterns of keratin intermediate filament and keratin associated protein genes in wool follicles Differentiation · 2009 · 95 citations
    2. Structure and Mechanical Properties of Human Trichocyte Keratin Intermediate Filament Protein Biomacromolecules · 2012 · 51 citations
    3. Cornification in reptilian epidermis occurs through the deposition of keratin‐associated beta‐proteins (beta‐keratins) onto a scaffold of intermediate filament keratins Journal of Morphology · 2012 · 33 citations
    4. Cryo-Electron Microscopy of Trichocyte (Hard α-Keratin) Intermediate Filaments Reveals a Low-Density Core Journal of Structural Biology · 2002 · 48 citations
    5. Structural Hierarchy of Trichocyte Keratin Intermediate Filaments Advances in experimental medicine and biology · 2018 · 15 citations
    6. The structure of human trichohyalin. Potential multiple roles as a functional EF-hand-like calcium-binding protein, a cornified cell envelope precursor, and an intermediate filament-associated (cross-linking) protein Journal of Biological Chemistry · 1993 · 161 citations
    7. A general mathematical model for the in vitro assembly dynamics of intermediate filament proteins Biophysical journal · 2022 · 5 citations
    8. Existence of trichohyalin-keratohyalin hybrid granules: Co-localization of two major intermediate filament-associated proteins in non-follicular epithelia Differentiation · 1994 · 54 citations
    9. Genes for intermediate filament proteins and the draft sequence of the human genome Journal of Cell Science · 2001 · 287 citations
    10. Regulation of a hair follicle keratin intermediate filament gene promoter Journal of Cell Science · 1998 · 39 citations
    11. Complete sequence of a hair-like intermediate filament type II keratin gene DNA sequence · 1993 · 15 citations
    12. Carbon-13 n.m.r. studies of keratin intermediate filament of human hair Polymer · 1998 · 5 citations
    13. Human Hair Keratin-Associated Proteins 2005 · 71 citations
    14. Effect of varied hair protein fractions on the gel properties of keratin/chitosan hydrogels for the use in tissue engineering Colloids and surfaces. B, Biointerfaces · 2020 · 41 citations
    15. Rational design of keratin nanoparticles utilizing diverse hair protein fractions for controlled drug release Journal of the Taiwan Institute of Chemical Engineers · 2023
    16. Isolation of intermediate filament assemblies from human hair follicles. The Journal of Cell Biology · 1985 · 28 citations
    17. Keratins: Dynamic, flexible structural proteins of epithelial cells Current problems in dermatology · 2001 · 13 citations
    18. Human hair keratin-associated proteins: Sequence regularities and structural implications Journal of Structural Biology · 2006 · 52 citations
    19. The proteomics of keratin proteins Journal of Chromatography B · 2006 · 62 citations
    20. Disulfide Cross-Linked Network Structure of Intermediate Filament and Matrix in Hair and Wool Cortices Sen'i Gakkaishi · 2015 · 4 citations
    21. Mutations in the helix termination motif of mouse type I IRS keratin genes impair the assembly of keratin intermediate filament Genomics · 2007 · 27 citations
    22. Bidirectional binding property of high glycine–tyrosine keratin-associated protein contributes to the mechanical strength and shape of hair Journal of structural biology · 2013 · 46 citations
    23. Identification of Novel Mutations in Basic Hair Keratins hHb1 and hHb6 in Monilethrix: Implications for Protein Structure and Clinical Phenotype Journal of Investigative Dermatology · 1999 · 62 citations
    24. The swelling behaviour of hair studied through the structural change of keratin protein during the permanent waving treatment Biophysical Chemistry · 2024
    25. Keratin function and regulation in tissue homeostasis and pathogenesis Biomolecular concepts · 2012 · 7 citations
    26. [Genetic and biochemical aspects of keratin synthesis by hair follicles]. PubMed · 2007 · 10 citations
    27. An in vitro analysis of the hemostatic efficacy of fibrinogen precipitation with varied keratin fraction compositions International journal of biological macromolecules · 2023 · 1 citations
    28. Proteopedia entry: Coiled‐coil structure of keratins Biochemistry and Molecular Biology Education · 2013 · 10 citations
    29. The human keratins: biology and pathology Histochemistry and Cell Biology · 2008 · 1398 citations
    30. Studies on the Proteome of Human Hair - Identification of Histones and Deamidated Keratins Scientific reports · 2018 · 54 citations