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The conclusion suggests a new treatment for infantile hemangiomas and a potential target for hair loss treatment.

Finasteride harms invertebrates' survival and burial ability.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

The hypothesis suggests that PCOS may start early in life due to genetic and environmental factors, influencing future reproductive and metabolic problems.

Targeting colon cancer stem cells might lead to better treatment results.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Alopecia areata, a common autoimmune hair loss condition, often runs in families.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

Dermoscopy helps diagnose and manage alopecia areata by showing specific hair changes.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Biotinidase deficiency has various symptoms and can be treated with biotin supplements.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Demodicosis is common and often missed, needing more recognition and treatment in skin care.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Too much androgen can cause hair loss; finasteride may help.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Male pattern baldness involves hormones and cell signals affecting hair growth.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.