Acute Disseminated Paracoccidioidomycosis with Molluscoid Lesions in a Young Woman

July 2015 in “ Actas Dermo-Sifiliográficas ”

Beatriz Di Martino Ortíz, Tatiana Moreno, G. Galeano, Mirtha Rodríguez

skin lesions histopathology lymph node smear amphotericin B itraconazole

TLDR A young woman with a rare fungal infection showed significant improvement after treatment with antifungal medication.

In 2015, a 21-year-old indigenous woman from Paraguay was diagnosed with acute disseminated Paracoccidioidomycosis (PCM), a fungal infection caused by Paracoccidioides brasiliensis. She had unusual molluscoid skin lesions on her face and systemic symptoms like fever, jaundice, and weight loss. Diagnosis was confirmed through histopathology and a lymph node smear. Treatment began with amphotericin B but was switched to itraconazole for 6 months due to kidney issues. The patient showed significant improvement after 2 months, with better skin and liver conditions, and no recurrence was noted. This case emphasizes the need to consider PCM in patients with skin lesions and systemic symptoms from endemic regions, regardless of their immunosuppression status.

View this study on sciencedirect.com →

Discuss this study in the Community →

Related Community Posts Join

6 / 1000+ results

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community What are these spots on my scalp

in Treatment 51 upvotes 4 months ago

A user noticed non-itchy, non-bleeding spots on their scalp while experiencing hair loss. Replies suggest the spots are likely sunspots or liver spots and recommend seeing a dermatologist; hair loss is attributed to male pattern baldness.

community Minoxidil Finasteride heart problems

in Update 97 upvotes 6 months ago

A user experienced heart problems after taking 1mg finasteride and 2.5mg oral minoxidil and is considering quitting minoxidil. Others discussed their experiences with heart issues and minoxidil, with some suggesting topical minoxidil as a safer alternative.

community For those of you who are getting facial skin side effects (aging, dark circles) from minoxidil, try this, it helped me.

in Minoxidil 11 upvotes 3 years ago

The conversation provides tips to reduce facial skin side effects from Minoxidil, such as changing pillowcases, sleeping on the back, careful application, hydration, and taking breaks. One reply suggests that alcohol in Minoxidil formulations, not Minoxidil itself, may cause skin aging.

community 5% Minoxidil after 4 months - started with twice a day but went down to once because I kept forgetting in the morning. Really happy with how it is going!

in Progress Pictures 438 upvotes 1 year ago

The conclusion of the conversation is that the user started using 5% Minoxidil for hair loss and is happy with the progress. They also mentioned being trans and coming off testosterone, which they believe will help prevent further hair loss. Some users suggested using finasteride as well.

community Oral minoxidil may not be as dangerous as what people say

in Minoxidil 9 upvotes 4 years ago

The safety of using oral minoxidil to treat hair loss and thinning, with studies showing mild side effects at low doses. It was suggested that people should consult a doctor or dermatologist before taking any type of medication for hair loss.

Similar Research

5 / 1000+ results

research Subject Index

March 2014 in “Journal of The American Academy of Dermatology”

The document lists various dermatology topics, treatments, and diagnostic methods.

research Dermatologic Diseases in Ferrets: Comprehensive Review and Treatment

7 citations, December 2011 in “Elsevier eBooks”

The document concludes that early diagnosis and treatment are crucial for managing skin diseases in ferrets.

research Prevalence, Clinical Characteristics, Possible Etiological and Diagnostic Approach in Dogs with Acral Lick Dermatitis

December 2022 in “Exploratory animal and medical research”

The study concluded that Acral lick dermatitis is most common in young male Labrador retrievers, often caused by psychological factors, and leads to skin inflammation and stress-related blood changes.

research Cutaneous Signals of Immune System Disease

May 1991 in “Current problems in dermatology”

Skin issues can indicate immune system problems.

research Cutaneous Manifestations of Systemic Infection in Children

May 1993 in “Current problems in dermatology”

Skin symptoms are important for diagnosing infections in children.