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Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.

Men with male-pattern baldness have more androgen receptors in their scalp's oil glands, which may contribute to hair loss.

A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.

Cyproterone acetate plus ethinyl estradiol is generally more effective in treating hirsutism, but consider side effects and patient characteristics.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.

Hair analysis for drugs needs a better understanding of how drugs enter hair, considering factors like hair structure and pigmentation.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Gefitinib can cause skin problems, diarrhea, and nausea, but rarely causes severe lung disease or hair loss.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

DA liposomes with chloramphenicol effectively target hair follicles and combat MRSA with minimal skin toxicity.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

The hair follicle pathway significantly affects how easily water-loving chemicals pass through the skin.

Finasteride and CPA-EE2 equally reduce hirsutism, but affect hormone levels differently.

Levetiracetam is widely used and generally well-tolerated for treating idiopathic generalized epilepsies, with tiredness as the main side effect.

pH, calcium, and reactive oxygen species regulate plant cell growth, with key roles for NADPH oxidases and plasma membrane H+-ATPases.

Minoxidil stimulates hair growth by increasing hair thickness and prolonging growth phase.

Cysteine-rich keratins evolved independently in mammals, reptiles, and birds for hard skin structures like hair, claws, and feathers.

White hair grows thicker and faster than black hair due to higher activity of growth-related genes and proteins.

High doses of finasteride cause cell growth and tumors in mice.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.

Minoxidil affects cell growth in two ways: low doses increase growth, while high doses slow it down and can be toxic.

Skin side effects from EGFR inhibitor cancer treatment can be managed effectively, often without stopping the medication.

LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.

The study concluded that PKP1 is essential for skin integrity and hair growth, and its dysfunction causes the symptoms of ectodermal dysplasia/skin fragility syndrome.

Activating NRF2 might help treat hair disorders by improving antioxidant defenses.