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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Polymeric nanoparticles show promise for treating skin diseases.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Lactate production is important for activating hair growth stem cells.

Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.

Researchers created human hair follicles using a new method that could help treat hair loss.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.