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Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.

Finasteride negatively affects fish reproduction and gonadal development.

The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Gender identity can be more diverse than just male or female.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Pediatric dermatologists need to understand the unique skin health needs of LGBTQIA youth to provide better care.

A 13-year-old with 46 XY DSD had ambiguous genitalia due to incomplete masculinization.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Certain drugs change freshwater snail shells to a "banana" shape.

Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

The document concludes that gender-affirming treatments are essential for transgender individuals and outlines safe hormone therapy practices.

The document does not determine if adults with aphallia are fertile.

Accurate gender and sex assessment in dermatology is essential for respectful and precise patient care.

Finasteride harms invertebrates' survival and burial ability.

A new genetic change causing early stop in the androgen receptor gene was found in a patient with androgen insensitivity syndrome.

Dermatologists are essential in helping transgender and gender diverse patients with skin and hair issues related to gender affirmation and hormone therapy.

Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.

A 20-year-old woman with a rare form of Turner syndrome showed improvement with hormonal therapy and needs comprehensive care.

Proxalutamide improved recovery, lowered death rates, and reduced hospital stay for COVID-19 patients.

More research is needed on the health effects of hormone therapy for transgender and nonbinary people.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Hormone therapy improves mental well-being in transgender individuals but requires ongoing health monitoring.

Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.