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    Glossary Interleukin-2

    regulates immune system by promoting T cell growth

    Interleukin-2 (IL-2) is a type of protein called a cytokine that plays a crucial role in the immune system. It helps regulate the activities of white blood cells, which are essential for fighting infections and diseases. IL-2 is particularly important for the growth, proliferation, and survival of T cells, a type of white blood cell that is vital for the body's immune response.

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    1. Dermatologic Changes Associated With Interleukin 2 Administration JAMA · 1987 · 123 citations
    2. Interleukin-25-Mediated-IL-17RB Upregulation Promotes Cutaneous Wound Healing in Diabetic Mice by Improving Endothelial Cell Functions Frontiers in Immunology · 2022 · 34 citations
    3. Recurrence of Pemphigus Vulgaris Associated With Interleukin 2 Therapy Archives of Dermatology · 1994 · 25 citations
    4. Evaluation of the level of serum Interleukins (IL-2, IL-4, IL-15 andIL-17) and its relationship with disease severity in patients with alopecia areata 2021 · 14 citations
    5. Assessment of Interleukin-17A and Interleukin-2 Serum Levels in Patients with Alopecia Areata Kufa Medical journal · 2024
    6. Effect of diode pumping solid state laser with wavelength 589 nm on gene expression of interlukine-2 and interferon-gamma Lowercase in human T-lymphocytes Journal of the Pakistan Medical Association · 2024
    7. Regularities of Change Concentrations of Interleukin-17A, Interleukin-2 and Interleukin-10 in the Blood of People with Alopecia Areata before and after Treatment with Platelet-Rich Plasma Ukraïnsʹkij žurnal medicini, bìologìï ta sportu · 2021
    8. Minoxidil downregulates Interleukin-1 alpha gene expression in HaCaT cells International Journal of Trichology · 2018 · 16 citations
    9. <i>Trichophyton tonsurans</i>‐induced kerion celsi with decreased defensin expression and paradoxically increased interleukin‐17A production The Journal of Dermatology · 2019 · 7 citations
    10. Interleukins gene polymorphism in alopecia areata patients: a systematic review 2025 · 1 citations
    11. Dandruff Is a Low‐Grade Inflammatory Condition Featuring Hyperproliferative Keratinocytes, Interleukin‐17‐Producing T Cells, and N‐Acyl Ethanolamines Immunity Inflammation and Disease · 2026
    12. Interleukin-1 Induces Transcription of Keratin K6 in Human Epidermal Keratinocytes 2001 · 90 citations
    13. Serum level of interleukin-15 in active alopecia areata patients and its relation to age, sex, and disease severity Advances in Dermatology and Allergology · 2020 · 14 citations
    14. Interleukin-15 and Tumor Necrosis Factor-α in Iraqi Patients with Alopecia Areata Dermatology Research and Practice · 2023 · 6 citations
    15. RETRACTED: Interleukin‐33 links asthma to alopecia areata: Mendelian randomization and mediation analysis Skin Research and Technology · 2024 · 4 citations
    16. Interleukin gene polymorphisms and alopecia areata: A systematic review and meta-analysis Medicine · 2024 · 2 citations
    17. Das weiße Hautfettgewebe initiiert die IL-33-abhängige Expression von Interleukin 4/13 in myeloischen Zellen während einer Entzündung Qucosa (Saxon State and University Library Dresden) · 2024
    18. Topische Immuntherapie mit Diphenylcyclopropenon bei verschiedenen Typen der Alpecia areata: Assoziation zu klinischen Parametern und einem funktionellen Genpolymorphismus des Interleukin-6-Promotors Elektronische Hochschulschriften der LMU München (Ludwig-Maximilians-Universität München) · 2005
    19. Impact of epidermal growth factor receptor and mitogen-activated kinase inhibition on hair follicles (HFs): partial HF immune privilege collapse and excessive interleukin-33 secretion British Journal of Dermatology · 2024 · 1 citations
    20. Elevated serum heat shock protein-70 and interleukin-15: prognostic biomarkers correlating with clinical severity and diagnostic efficacy in active alopecia areata Journal of the Egyptian Womenʼs Dermatologic Society · 2026
    21. The many faces of interleukin-17 in inflammatory skin diseases 2016 · 77 citations
    22. Tumor Necrosis Factor-α and Interleukin-1 Antagonists Alleviate Inflammatory Skin Changes Associated with Epidermal Growth Factor Receptor Antibody Therapy in Mice Cancer Research · 2009 · 53 citations
    23. The association between Interleukin (IL)-4 gene intron 3 VNTR polymorphism and alopecia areata (AA) in Turkish population Gene · 2013 · 42 citations
    24. Testosterone stimulates proliferation and inhibits interleukin‐6 production of normal and hereditary gingival fibromatosis fibroblasts Oral Microbiology and Immunology · 2002 · 39 citations
    25. Activation of liver X receptors inhibits experimental fibrosis by interfering with interleukin-6 release from macrophages Annals of the Rheumatic Diseases · 2014 · 36 citations
    26. Interleukin-10-deficient Mice Are Less Susceptible to the Induction of Alopecia Areata Journal of Investigative Dermatology · 2002 · 31 citations
    27. Association Between Interleukin 18 Polymorphisms and Alopecia Areata in Koreans Journal of Interferon & Cytokine Research · 2014 · 22 citations
    28. Alopecia Diffusa while Using Interleukin-17 Inhibitors against Psoriasis Vulgaris Case Reports in Dermatology · 2019 · 20 citations
    29. Interleukin-6 Null Mice Paradoxically Display Increased STAT3 Activity and Wound-Induced Hair Neogenesis Journal of Investigative Dermatology · 2016 · 16 citations
    30. Interleukin-6 from Adipose-Derived Stem Cells Promotes Tissue Repair by the Increase of Cell Proliferation and Hair Follicles in Ischemia/Reperfusion-Treated Skin Flaps Mediators of inflammation · 2019 · 14 citations