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    Glossary Interferon-alpha

    protein that boosts immune response against viruses and cancer

    Interferon-alpha (IFN-α) is a type of protein produced by the body's immune system in response to viral infections. It helps to inhibit viral replication and modulate the immune response, making it a crucial component in the body's defense against pathogens. Clinically, IFN-α is used in the treatment of various conditions, including certain types of cancer and viral infections like hepatitis C.

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    1. Alopecia areata during Interferon Alpha-2b/Ribavirin Therapy Dermatology · 2002 · 35 citations
    2. Predictive factors for adverse dermatological events during pegylated/interferon alpha and ribavirin treatment for hepatitis C Journal of Clinical Virology · 2014 · 11 citations
    3. Exacerbation of alopecia areata during pegylated interferon alpha-2b and ribavirin therapy, possibly due to the collapse of hair follicle immune privilege European Journal of Dermatology · 2014 · 10 citations
    4. Interferon alpha 2B Reactions Weekly · 1992
    5. Clinical Characteristics and Factors Associated with Hair Loss Severity in Chronic Hepatitis B Patients Receiving Pegylated Interferon-Alpha: A Retrospective Cohort Study Clinical Cosmetic and Investigational Dermatology · 2026
    6. A Prospective Study of Cutaneous Adverse Events Induced by Low-Dose Alpha-Interferon Treatment for Malignant Melanoma Dermatology · 2004 · 56 citations
    7. Tumour Necrosis Factor Alpha, Interferon Gamma and Substance P Are Novel Modulators of Extrapituitary Prolactin Expression in Human Skin PLOS ONE · 2013 · 24 citations
    8. Lichenoid dermatitis from interferon alpha-2a in a patient with metastatic renal cell carcinoma and seronegative HCV Journal of The American Academy of Dermatology · 2016 · 4 citations
    9. Bullous Lesions at Polyethylene Glycol Interferon-alpha-2a Inoculation Site in a Hepatitis C Virus-infected Subject Acta Dermato Venereologica · 2007 · 2 citations
    10. Segmental Vitiligo and Hair Curling After Interferon α and Ribavirin Treatment for Hepatitis C Skinmed · 2006 · 14 citations
    11. The influence of interferon on healthy and diseased skin Cytokine · 2018 · 32 citations
    12. Pegylated-interferon-α<sub>2a</sub>in clinical practice: how to manage patients suffering from side effects Expert Opinion on Drug Safety · 2011 · 17 citations
    13. Alopesi areata hastalarında serum interferon-gama, tümör nekrozis faktör-alfa, interlökin-13, interlökin-17 ve transforming growth faktör-beta düzeylerinin değerlendirilmesi 2016
    14. Identification of xenobiotics interfering with 5 <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline" id="d1e152" altimg="si21.svg"> <mml:mi>α</mml:mi> </mml:math> -reductase (SRD5A2) activity Toxicology Letters · 2026
    15. Current management strategies for cutaneous T-cell lymphoma Clinics in Dermatology · 2004 · 39 citations
    16. Skin diseases associated with hepatitis C virus: Facts and controversies Clinics in Dermatology · 2010 · 27 citations
    17. Intralesional therapy for the treatment of keratoacanthoma Dermatologic therapy · 2019 · 25 citations
    18. Treatments for alopecia areata: A systematic review and network meta‐analysis Dermatologic therapy · 2021 · 23 citations
    19. Zinc: A complementary factor in the treatment of chronic hepatitis C? (Review) Molecular Medicine Reports · 2010 · 21 citations
    20. Case Report: Diffuse Hypertrichosis in the Course of Hepatitis C Treatment by IFN-<i>α</i> and Ribavirin Journal of Interferon and Cytokine Research · 2002 · 16 citations
    21. Immunomodulators in the treatment of cutaneous lymphoma Journal of the European Academy of Dermatology and Venereology · 1999 · 11 citations
    22. Hepatitis C Treatment and Alopecia Totalis Journal of Investigative Dermatology Symposium Proceedings · 2013 · 8 citations
    23. Off-label use of biologics and janus kinase (JAK) inhibitors for scarring alopecias: a narrative review Archives of Dermatological Research · 2025 · 3 citations
    24. Reply Journal of The American Academy of Dermatology · 1997 · 2 citations
    25. Widespread Dystrophic-Anagen Alopecia and Drug Eruption due to Usage of PEG-IFN ?-2a /Ribavirin Combination Therapy Hair therapy & transplantation · 2014 · 1 citations
    26. Plasmacytoid dendritic cells as a key player in the initiation phase of alopecia areata-induced C3H/HeJ mouse Journal of Dermatological Science · 2016
    27. THERAPEUTIC CHALLENGES IN POLYAUTOIMMUNITY: ANIFROLUMAB FOR LUPUS ERYTHEMATODES IN OVERLAPPING AUTOIMMUNE SYNDROMES The Journal of Rheumatology · 2025
    28. Resolution of advanced conjunctival squamous cell carcinoma with cemiplimab immunotherapy, IFNα-2b, and retinoic acid treatment over 2 years of follow-up Canadian Journal of Ophthalmology · 2024
    29. Correspondence Journal of The European Academy of Dermatology and Venereology · 1998
    30. Dermatologic therapy: December 1986 to December 1987 Journal of The American Academy of Dermatology · 1988