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Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Zinc is effective for treating various skin conditions, including warts and acne.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Hair loss can significantly affect a person's self-esteem and body image, especially in young people, those who value their looks highly, and women.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Fat cells in the skin help start healing and form important repair cells after injury.

Diffuse alopecia in women may be related to androgens and iron deficiency, and basic hormone and nutrient screening is useful.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

A specific drug can help treat Lichen Planopilaris, a condition causing permanent hair loss.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

The Protein-Sparing Modified Fast is effective for rapid weight loss and maintaining it, but requires medical supervision and can have side effects.

Spironolactone is effective for treating acne, hirsutism, and androgenic alopecia in women with few side effects.

A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.

Mouflon rams mature gradually with changes in body, horns, and hormones linked to age and seasons, reaching full sexual maturity well after puberty.

Minoxidil quickly leaves blood, turns into urine metabolites, and has lasting blood pressure-lowering effects.