research The Densities of T Cells, Langerhans Cells, and Natural Killer Cells in Uninvolved Skin of Patients with Acne Vulgaris
People with acne have more CD4+ immune cells in their skin than healthy people.
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research Teriflunomide (Aubagio) for the Treatment of Multiple Sclerosis
Teriflunomide is an effective and generally safe oral treatment for relapsing MS, reducing relapses and slowing disability progression.
research Biomaterials for Dermal Substitutes
The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.
research Bioengineering Skin Using Mechanisms of Regeneration and Repair
Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
research The Role of Macrophages in Skin Homeostasis
Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.
research Immune Deficiency-Related Enteropathy-Lymphocytopenia-Alopecia Syndrome Results from Tetratricopeptide Repeat Domain 7A Deficiency
A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.
research Imbalance of T-Helper 17 and Regulatory T Cells in Patients with Alopecia Areata
People with alopecia areata have more Th17 cells and fewer Treg cells, which may be key to the condition's development.
research iNKT Cells Ameliorate Human Autoimmunity: Lessons from Alopecia Areata
iNKT cells can help prevent and treat alopecia areata by promoting hair regrowth.
research Effects of Imiquimod on Hair Follicle Stem Cells and Hair Cycle Progression
Imiquimod cream activates hair follicle stem cells and causes early hair growth by changing immune cells and certain protein expressions.
research Telogen Effluvium as a Sign of Hodgkin Disease
Hair loss may be an early sign of serious illnesses like Hodgkin disease.
research Antroquinonol Exerts Immunosuppressive Effect on CD8+ T Cell Proliferation and Activation to Resist Depigmentation Induced by H2O2
Antroquinonol may help prevent skin depigmentation by suppressing certain immune cells.
research Identification of Distinct Immune Signatures and Chemokine Networks in Scalp Inflammatory Diseases
Different immune responses cause hair loss in scalp diseases, with unique patterns in scalp psoriasis possibly protecting against hair loss.
research Scalp Psoriasis: Alopecia and Treatment Challenges
Scalp psoriasis can cause different types of hair loss, with some patients developing permanent hair loss, and treatment may be stopped due to skin reactions.
research Chromatin Architectural Protein CTCF Controls Epidermal Barrier Formation, Hair Follicle Fate Maintenance, and Suppresses Inflammatory Responses in the Skin Epithelium
The protein CTCF is essential for skin development, maintaining hair follicles, and preventing inflammation.
research Effect of High-Fructose Diet on the Renal Cortex of Adult Male Albino Rats
High-fructose diets can cause irreversible kidney damage.
research Alopecia in Laboratory Animals Induced by a Polyampholyte, Polyethylene Alanine
Polyethylene alanine caused hair loss in young lab animals but not in adults, with hair regrowth occurring within 20 days.
research Simvastatin Decreases Alopecia Areata-Associated Inflammation Through Effects on Isoprenoid Metabolites
Simvastatin reduces inflammation and promotes hair regrowth in alopecia areata.
research Follicular Dysplasia and Hair Loss in White-Tailed Deer (Odocoileus Virginianus)
White-tailed deer can get a hair loss condition that might make them more vulnerable to environmental threats.
research Autoimmune Alopecia Areata Due to Thymoma Without Myasthenia Gravis: A Case Report
A woman's hair loss improved after removing a tumor in her thymus gland, suggesting hair loss can be linked to such tumors even without a specific muscle weakness condition.
research Atypical Presentation of Lichen Planopilaris: Presentation of Two Cases and Review
Two unusual cases showed that Lichen Planopilaris can look like other skin conditions and need early treatment to protect hair.
research Epidemiological, Clinical, Trichoscopic, and Histopathological Features of Lupus Erythematosus Mimicking Alopecia Areata: A Multicenter Retrospective Study
Lupus erythematosus can mimic alopecia areata, and trichoscopy is key for accurate diagnosis and better patient outcomes.
research Dermatopathology Quiz: Which Alopecia Does the Patient Have?
The patient has frontal fibrosing alopecia (FFA).
research Resident Memory T Cells in Autoimmune Skin Diseases
Certain immune cells contribute to skin autoimmune diseases, and some treatments can reverse hair loss in these conditions.
research Selective Inhibition of JAK3 Signaling Is Sufficient to Reverse Alopecia Areata
Blocking JAK3 signaling can reverse hair loss from alopecia areata.
research Consumption of Fish Oil High-Fat Diet Induces Murine Hair Loss via Epidermal Fatty Acid Binding Protein in Skin Macrophages
Eating a high-fat fish oil diet caused mice to lose hair due to a specific immune cell activity in the skin linked to a protein called E-FABP.
research AIRE Deficiency Leads to the Development of Alopecia Areata-Like Lesions in Mice
AIRE deficiency causes hair loss similar to alopecia areata in mice.
research Pathogenesis of Alopecia Areata and Vitiligo: Commonalities and Differences
Alopecia areata and vitiligo share immune system dysfunction but differ in specific immune responses and affected areas.
research Recurrent Pseudolymphomatous Reaction to Ear Piercing: 20-Year History
A woman had a rare reaction to ear piercing that caused earlobe swelling, which was best treated by removing the piercing and not re-piercing.
research Alopecias: Practical Tips for the Management of Biopsies and Main Diagnostic Clues for General Pathologists and Dermatopathologists
The document concludes that understanding hair follicle histology and the hair cycle is crucial for diagnosing alopecia.
research Demographic and Histopathological Evaluation in 71 Patients Diagnosed with Dissecting Cellulitis of the Scalp
Dissecting Cellulitis of the Scalp is more common in young men and often associated with head and neck acne.