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Innovative methods are reducing animal testing and improving biomedical research.

Hashimoto thyroiditis is an autoimmune disease that can lead to an underactive thyroid and is treated with medication and sometimes diet changes or surgery.

Active oxygen scavengers can reverse the suppression of hair cell growth caused by androgens.

Different substances affect hair and skin cell growth in various ways.

Different substances affect hair and skin cell growth in various ways, with some promoting and others inhibiting cell proliferation.

Cyclosporin A and FK506 can start new hair growth in mice, but ascomycin and rapamycin cannot.

Polycystic Ovary Syndrome should be seen mainly as a condition of excess male hormones, with a focus on this in its definition.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

Rosacea is a skin condition with unclear causes, classified into four subtypes.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

Fat tissue-derived cells show promise for repairing body tissues, but more research and regulation are needed for safe use.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Polymeric nanoparticles show promise for treating skin diseases.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Hidradenitis suppurativa, a chronic skin disease, can be managed with antibiotics, lifestyle changes, and in severe cases, surgery. Early diagnosis and careful planning are key, and laser treatment can be an efficient solution for mild to severe cases.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.