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    Glossary Immune Regulation

    processes that control immune system activity and balance

    Immune Regulation, also known as immune system regulation or regulation of immune response, refers to the complex processes that control the activity and balance of the immune system. This involves mechanisms that activate immune responses to fight infections and diseases, as well as those that suppress these responses to prevent overactivity that could lead to autoimmune diseases, such as alopecia areata, where the immune system mistakenly attacks hair follicles.

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    1. Plasma proteome–driven identification of druggable immune regulators of alopecia areata, validated by transcriptome and single-cell mapping Skin Appendage Disorders · 2026
    2. Supplementary Material for: Plasma proteome–driven identification of druggable immune regulators of alopecia areata, validated by transcriptome and single-cell mapping Figshare · 2026
    3. Supplementary Material for: Plasma proteome–driven identification of druggable immune regulators of alopecia areata, validated by transcriptome and single-cell mapping Figshare · 2026
    4. 496 Identification of differentially expressed miRNAs in alopecia areata that target immune-regulatory pathways 2017
    5. Construction of regulatory network for alopecia areata progression and identification of immune monitoring genes based on multiple machine-learning algorithms Precision clinical medicine · 2023 · 3 citations
    6. Regulatory T cells in skin mediate immune privilege of the hair follicle stem cell niche Science Immunology · 2024 · 21 citations
    7. The imbalance between Type 17 T-cells and regulatory immune cell subsets in psoriasis vulgaris Frontiers in Immunology · 2022 · 49 citations
    8. Beyond immune suppression: regenerative programs in regulatory T cells Cell Insight · 2026
    9. An immune regulatory CCT repeat containing oligodeoxynucleotide capable of causing hair loss in male mice Human & Experimental Toxicology · 2016
    10. 546 Epidermal growth factor receptor as a key regulator of the immune privilege Journal of Investigative Dermatology · 2022
    11. Dermal T cell immunity and key regulatory signaling pathways: Implications in immune-mediated alopecia and hair regeneration Genes & Diseases · 2025 · 1 citations
    12. Hair Follicle Mesenchyme-Associated PD-L1 Regulates T-Cell Activation Induced Apoptosis: A Potential Mechanism of Immune Privilege Journal of Investigative Dermatology · 2013 · 53 citations
    13. Regulatory T cells: master orchestrators of immune tolerance and tissue homeostasis Frontiers in Science · 2026 · 2 citations
    14. 1432 IL-9/IL-9R signaling as a novel regulator of human hair follicle growth and immune privilege Journal of Investigative Dermatology · 2023
    15. Repigmentation Competence in Vitiligo: Integrating Immune, Regulatory, Regenerative, and Microenvironmental Axes Journal of Personalized Medicine · 2026
    16. Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells Journal of immunology research · 2019 · 47 citations
    17. Internal peacekeepers and external mediators: A new model of peripheral immune tolerance involving regulatory T cells and mesenchymal stem cells Advances in Clinical and Experimental Medicine · 2026
    18. Identification of differentially expressed miRNAs in alopecia areata that target immune-regulatory pathways Genes and immunity · 2017 · 14 citations
    19. Advancements in research on the immune-inflammatory mechanisms mediated by NLRP3 inflammasome in ischemic stroke and the regulatory role of natural plant products Frontiers in Pharmacology · 2024 · 18 citations
    20. AP-2α/AP-2β transcription factors are key regulators of epidermal homeostasis bioRxiv (Cold Spring Harbor Laboratory) · 2023
    21. Disturbance of Immune Microenvironment in Androgenetic Alopecia through Spatial Transcriptomics International Journal of Molecular Sciences · 2024
    22. Regulatory T Cells in Autoimmune Diseases and their Potential Journal of Investigative Dermatology Symposium Proceedings · 2005 · 3 citations
    23. FOXP3 <sup>+</sup> regulatory T cells and age‐related diseases FEBS Journal · 2021 · 26 citations
    24. 0009 Regulatory γδ T cells protect human scalp hair follicles from alopecia areata in vivo and represent potential therapeutic target Journal of Investigative Dermatology · 2025
    25. 001 Human scalp hair follicles are protected from alopecia areata in vivo by regulatory γδT cells Journal of Investigative Dermatology · 2024
    26. Human regulatory γδT lymphocytes as novel autoimmunity-protective cells: Lessons from alopecia areata 2024
    27. 52993 Regulatory γδ T cells protect human scalp hair follicles from alopecia areata in vivo Journal of the American Academy of Dermatology · 2024
    28. 185 Regulatory γδ T cells protect human scalp hair follicles from alopecia areata in vivo Journal of Investigative Dermatology · 2023
    29. Tracing immune cells around biomaterials with spatial anchors during large-scale wound regeneration Nature Communications · 2023
    30. Hair follicle immune privilege and its collapse in alopecia areata Experimental dermatology · 2020 · 134 citations