20 citations
,
August 2017 in “Drug testing and analysis” This study used micro-segmental hair analysis to identify the day of drug intake and suggested differing uptake mechanisms for co-administered drugs based on their properties.
42 citations
,
May 2003 in “Mini-reviews in Medicinal Chemistry” This study found that newly synthesized steroidal trienones demonstrated stronger 5α-reductase inhibitory activity compared to dienones in various biological models, suggesting potential for developing enhanced antiandrogenic drugs.
This study observed that intramuscular injection of sodium 131iodide at doses of up to 1 mCi can successfully induce hypothyroidism in rats without significantly damaging muscle or nearby tissues, despite concerns of adverse effects.
December 2025 in “International Journal of Pharmaceutics” PLGA-based microneedles show promise for painless, long-term drug delivery but need design and safety improvements.
8 citations
,
June 1995 in “Helvetica Chimica Acta” This article outlines the synthesis of spiro[cyclohexane‐1,2′‐[2 H ]indene] derivatives similar to known steroid 5α‐reductase inhibitors, but it does not report experimental findings.
September 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that finasteride reduced opioid self-administration in zebrafish and rats without affecting pain relief, suggesting steroidogenic pathways may offer new treatment avenues for opioid use disorder.
20 citations
,
June 1995 in “Tetrahedron Letters” This study reported that newly synthesized phenanthridin-3-one derivatives effectively inhibit human steroid 5-α-reductase.
57 citations
,
December 1960 in “Archives of Dermatology” This introduction reviews historical use of steroids for alopecia treatment, mentioning early cases of hair regrowth with cortisone acetate but provides no new clinical data.
13 citations
,
May 2011 in “Bioorganic & Medicinal Chemistry” This study identified certain benzopyran derivatives with a bulky tert-butyloxycarbonylamino group as effective KATP channel openers that inhibit insulin secretion in rat pancreatic islets.
76 citations
,
January 2022 in “Journal of Tissue Engineering” This review summarizes recent progress in microneedle-based drug delivery systems and discusses their potential impact on cellular mechanisms and immunization signaling pathways, highlighting the need for further development in fabrication methods.
10 citations
,
May 2016 in “Polymer” This study reports that novel core-ABS nanocarriers efficiently loaded with dexamethasone and finasteride show potential for dermal drug delivery, exhibiting non-toxic interactions with human keratinocyte cells and skin penetration.
324 citations
,
July 2020 in “Applied Water Science” This study found high levels of toxic heavy metals in water sources of mining communities in Abakaliki, Nigeria, posing potential health risks including Parkinson's and Alzheimer's diseases.
254 citations
,
September 2014 in “Menopause” The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.
61 citations
,
May 2015 in “Planta” Certain fungi and bacteria help orchid seeds germinate and plants grow better.
60 citations
,
December 2005 in “Biomedical Papers” This article reviews hair analysis for drug detection and its applications in various fields, but reports no new research findings, emphasizing the need to consider the method's complexities and potential pitfalls.
56 citations
,
January 2019 in “Lancet” This review discusses the emerging use of JAK inhibitors in alopecia areata treatment and reports no new clinical results; it highlights hair regrowth despite symptom recurrence after stopping therapy.
36 citations
,
October 2016 in “Bone” This case report describes a male patient with aromatase deficiency, revealing that a c.628G>A mutation can lead to varied clinical features, such as low bone mass and normal metabolic profiles.
27 citations
,
June 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified numerous size polymorphisms in the human ultrahigh sulfur KAP4 genes due to intragenic sequence variations, suggesting these polymorphisms may have arisen through deletions and duplications during evolution.
23 citations
,
December 2009 in “International Journal of Sport Management and Marketing” This paper examines crisis management models within sport marketing and sponsorship, focusing on the brand risks of athlete-triggered crises, and calls for further research in this area; it does not report new results.
21 citations
,
June 2020 in “Dermatologic Therapy” This study found a marked decrease in dermatology outpatient visits during the initial two months of COVID-19, with shifts in diagnosis frequencies for conditions like generalized pruritus and alopecia areata.
21 citations
,
March 2019 in “Journal of The American Academy of Dermatology” This review discusses the dermatologic care of transgender individuals and highlights the need for more quantitative research to improve clinical understanding and support future studies.
19 citations
,
February 2012 in “International Journal of Urology” This review discusses gender identity disorder in Japan, highlighting the high prevalence and challenges in accessing appropriate treatment, and calls for wider understanding among medical professionals.
18 citations
,
March 1985 in “Journal of The American Academy of Dermatology” Cocaine use can cause a blistering skin disease.
16 citations
,
April 2011 in “Journal of The American Academy of Dermatology” This article overviews dermatologic findings in forensic pathology and reports no new results; it emphasizes the importance of recognizing skin manifestations in identifying types of injury.
15 citations
,
May 2005 in “Seminars in Plastic Surgery” This article details techniques for eyebrow and eyelash reconstruction surgery with hair follicular unit transplantation but reports no new clinical results; the author describes the advantages over other methods.
14 citations
,
November 2020 in “International Journal of Molecular Sciences” This review article summarizes the potential role of advanced medical therapies—using genes, cells, and/or tissue engineering—in treating various types of alopecia, by examining clinical research, basic studies, and ongoing trials.
13 citations
,
March 2013 in “Dermatologic Surgery” This review discusses the evolution and current practices of Follicular Unit Extraction (FUE) in hair restoration surgery, reporting comparable patient outcomes to Follicular Unit Transplantation (FUT), though noting controversies in its adoption.
12 citations
,
January 2024 in “Editora In Vivo eBooks” This case report from the study describes a dog suffering from dermatophytosis caused by Microsporum canis, presenting with alopecia on the neck and ear, illustrating the zoonotic risk of these fungal infections in both animals and humans, particularly in hot and humid climates.
12 citations
,
January 2007 in “Acta dermato-venereologica” This review discusses the classification and regulation challenges of anti-ageing cosmetics in Europe and reports no new findings; it calls for increased transparency to help consumers make informed choices.
11 citations
,
January 2016 in “Journal of clinical & experimental dermatology research” This review discusses the cutaneous manifestations associated with various substances of abuse, highlighting their importance for clinicians in recognizing and treating substance abuse disorders, and reports no new findings.