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This study suggests that in rat skin, testosterone itself may play a more significant role in androgen action than 5α-dihydrotestosterone, unlike in the prostate where 5α-DHT is more dominant.

This review discusses testosterone metabolism in human skin and its link to androgenetic alopecia, acne vulgaris, and idiopathic hirsutism, but it presents no new results.

This study suggests that gender-affirming testosterone therapy in transgender men is generally safe and effective with adequate screening and monitoring, although high-quality long-term studies are lacking.

In this study, bilateral oophorectomy was reported as an effective treatment for normalizing androgen levels and resolving hypersexuality and related symptoms in a post-menopausal woman with ovarian hyperthecosis, suggesting its importance in addressing excess androgen production in such cases.

This study found that c-Maf positive M2 macrophages may promote hypertrophic scar formation by enhancing the proliferation, migration, and extracellular matrix deposition of hypertrophic scar fibroblasts through increased TGF-β1 expression.

This case report describes a Canadian Husky dog with sertolioma that exhibited dermatological symptoms and aggressive behavior, both of which improved significantly after surgery.

The case showed the need for quick investigation of virilization in women and how emotional health is linked to physical health.

This case series describes young men with mild scalp psoriasis and a family history of androgenetic alopecia who exhibit a compulsive behavior of preserving scalp scales, highlighting a potential body-focused repetitive behavior.

This case report describes a 36-year-old Pakistani phenotypic female diagnosed with 46,XY 5-alpha-reductase deficiency, highlighting that such disorders of sexual development can manifest with symptoms like obesity, hirsutism, and amenorrhea later in life due to unique circumstances.

In this study, men seeking treatment for male pattern hair loss were highly concerned about their condition and had often attempted self-treatment, but many were dissatisfied with their physician consultations due to unmet expectations and perceived indifference from doctors.

This study found that in patients with severe aortic valve stenosis, higher serum dihydrotestosterone levels were associated with increased myocardial hypertrophy, fibrosis, and reduced left ventricular function.

This review discusses the negative effects of anabolic androgenic steroids on various organ systems in men and reports no new results, highlighting the need for physician awareness.

This study reviewed research on the psychosocial effects of gender-affirming dermatology treatments in transgender populations, finding mostly positive associations but noting significant limitations and the need for more comprehensive studies to clearly understand these effects.

This literature review highlights varying recommendations for testosterone use in peri- and postmenopausal women, noting its accepted role in treating hypoactive sexual desire disorder but stressing controversy and lack of FDA-approved options for broader use.

This study suggests that some men with premature androgenic alopecia may have hormonal profiles similar to women with polycystic ovary syndrome, potentially indicating a male equivalent of the condition.

This study concluded that higher androgen levels in males and specific skeletal sites may contribute to differences in skeletal morphology, with glucocorticoids, E2, and D3 enhancing androgen receptor expression and mitogenic action in human osteoblastic cells.

This study found that while many women were aware of some symptoms and causes of androgen excess, there is a need to improve education on this endocrine disorder, especially among those without medical backgrounds.

This review discusses how androgens, commonly known for male reproductive roles, also influence the physiology and pathology of the human endometrium, though their exact roles in this tissue remain controversial and not fully understood.

This review discusses the role of androgens in menopausal women's health, highlighting symptoms of both hyperandrogenemia and androgen deficiency, but reports no clinical results.

This review discusses skin diseases in transgender patients receiving gender-affirming hormone therapy and procedures, highlighting unique conditions and the underdiagnosis that affects their quality of life and mental health.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

In PCOS, high male hormones cause hair growth, acne, and hair loss, affecting periods.

This study suggests that hepatocellular carcinoma in cirrhotic men is associated with altered sex-steroid metabolism, indicated by lower testosterone and 5 alpha-dihydrotestosterone levels compared to cirrhosis alone.

This review discusses the role of anti-Müllerian hormone in polycystic ovary syndrome and its male equivalent, but reports no new clinical findings; it suggests further investigation is needed into male relatives' reproductive function.

This study reported that there are no standardized guidelines for managing testosterone-induced acne vulgaris and androgenic alopecia in transmasculine or non-binary individuals undergoing gender-affirming hormone therapy, highlighting gaps in dermatology trainees’ preparedness to care for this population.

The body's change of testosterone into DHT is not necessary for testosterone's muscle and sexual effects.