June 2026 in “EJC Paediatric Oncology” In this retrospective study on pediatric craniospinal irradiation, researchers found that permanent radiation-induced alopecia occurred in 45.8% of patients, with higher radiation doses and treatment intensity being significant predictors, suggesting that defined dosimetric thresholds can support scalp-sparing planning.
10 citations
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June 2010 in “Fertility and Sterility” In this study, patients with polycystic ovary syndrome self-reported higher hirsutism scores compared to clinician assessments, but only clinician scores correlated with biochemical markers of hyperandrogenism.
22 citations
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August 2011 in “Endocrine Practice” This review discusses the etiology, diagnosis, and management strategies for hirsutism, noting that serious underlying disorders are rare and emphasizing targeted treatment to manage testosterone's effects.
November 2022 in “Journal of Investigative Dermatology” This study found that human scalp hair follicles produce neurohormones and responded to GHRH stimulation by prolonging hair growth, suggesting a functional peripheral HPS neuroendocrine signaling axis in the skin.
April 2025 in “The Journal of Clinical Endocrinology & Metabolism” This study highlights the global prevalence of hirsutism in women and reviews its diagnostic criteria, potential underlying causes like polycystic ovary syndrome, and treatment options, emphasizing the need for tailored, multifaceted management and acknowledging the distress it causes patients.
March 2005 in “Journal of The American Academy of Dermatology” Diphencyprone treatment protocols could be simplified as no harm occurred despite not fully following them.
2 citations
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November 2021 in “International Journal of Current Pharmaceutical Research” This review discusses the pathogenesis, causes, and treatments of hirsutism but provides no new clinical findings; the authors emphasize the strong impact of hirsutism on quality of life.
This review discusses the evaluation and treatment options for hirsutism, including both cosmetic and pharmacological interventions, but reports no new research findings.
April 2023 in “Expert opinion on pharmacotherapy” This review article concluded that combined oral contraceptive pills and antiandrogens are the most effective pharmacotherapy for improving hirsutism, while physical therapies and psychological support are essential for optimal management.
October 2023 in “Acta Medica Nicomedia” In this study, hirsutism negatively affected quality of life in Turkish patients, as measured by the Dermatology Life Quality Index, although no significant relationship was observed between the severity of hirsutism and quality of life scores.
September 1996 in “Hair transplant forum international” This article discusses the rapid advancements in hair restoration surgery presented at ISHRS Annual Meetings and underscores the difficulty of staying updated without attending, but it reports no new experimental findings.
3 citations
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August 2017 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found that women with PCOS had significantly elevated plasma levels of PAI-1, which correlated with insulin resistance and obesity.
11 citations
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January 2023 in “World Journal of Clinical Cases” This study suggests that idiopathic hirsutism may involve higher local androgen synthesis despite normal serum androgen levels, challenging its categorization as idiopathic.
378 citations
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November 2011 in “Human reproduction update” This review discusses the epidemiology, causes, diagnosis, and management of hirsutism in women, noting that effective treatment requires addressing the root cause as well as the hair growth.
9 citations
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August 2023 in “Molecules” This study found that the peptides RMYYY and VMYMI displayed stronger binding energy and more frequent interactions with HPGDS compared to the native inhibitor, suggesting potential as future therapeutic drugs.
April 2024 in “Middle East Fertility Society Journal” In this study of infertile Indonesian women with PCOS, researchers found no correlation between hirsutism, body measurements, and sexual dysfunction scores, but noted that hirsutism may be linked to higher anxiety levels.
118 citations
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May 2015 in “European journal of pharmaceutics and biopharmaceutics” This study found that the pH-sensitive hydrogel HECHA13, containing isoliquiritigenin, effectively inhibited the growth of Propionibacterium acnes and showed promise for transdermal delivery in acne treatment.
1 citations
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July 2006 in “Reviews in gynaecological and perinatal practice” This review explores various therapeutic options for managing female hirsutism, emphasizing the effectiveness of low-dose finasteride and cyproterone acetate, but it presents no new clinical results.
49 citations
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September 2012 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This review discusses the physiology of hair growth, common abnormal patterns of hirsutism, and examines differential diagnoses and treatment options, but provides no new clinical findings.
January 2023 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that hirsutism is a prevalent cosmetic issue among Iraqi women, with most cases being idiopathic and a significant portion having a familial history.
20 citations
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January 2012 in “International Journal of Trichology” This study identified polycystic ovarian syndrome as the most common cause of hirsutism among patients and found a positive correlation between hirsutism severity and free testosterone levels.
55 citations
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March 2000 in “American journal of clinical dermatology” Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.
11 citations
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January 2015 in “Modern Chemistry & Applications” This study found hirsutism negatively affects quality of life and psychological wellbeing in women, suggesting effective medical treatment alongside psychotherapy might better address these issues than psychotherapy alone.
29 citations
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September 2004 in “Fertility and Sterility” This study found that an intermittent low-dose regimen of finasteride (2.5 mg every 3 days) effectively reduced hirsutism scores in women with idiopathic hirsutism or polycystic ovary syndrome, with fewer side effects than continuous daily administration.
August 2025 in “PLoS ONE” This review explores treatment options for HS in the US and identifies how social disparities impact access to care, but it reports no new clinical findings.
61 citations
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January 2017 in “Human Reproduction Open” This review discusses hormone replacement therapy for women with premature ovarian insufficiency, strongly recommending it for symptom relief and bone protection, but notes a lack of evidence on optimal types and doses.
This study of hirsutism in Chennai found idiopathic causes most common and reported that both Nd YAG and IPL lasers had a 70% good response rate in hair removal across different skin types.
November 2006 in “Hair transplant forum international” This announcement promotes the ISHRS 15th Annual Scientific Meeting in Las Vegas, detailing its status as a leading event for hair restoration, and contains no research findings.
27 citations
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July 2009 in “Experimental and Clinical Endocrinology & Diabetes” This study found that finasteride significantly improved hirsutism scores in women over 12 months and was well-tolerated with no serious side effects.