Scalp Segmentation and Permanent Alopecia Prediction in Pediatric Craniospinal Irradiation: The PAST and HOPE Projects

    June 2026 in “ EJC Paediatric Oncology
    Camilla Satragno, Gianluca Piccolo, Federica Picichè, Mattia Barboro, Irene Schiavetti, Sucheeta Campora, A. Alparone, Stefania Zara, Daniele Zefiro, F. Cavagnetto, Marta Molteni, Claudia Mercuri, Flavio Giannelli, Claudia Milanaccio, Salvina Barra, Antonio Verrico, Liliana Belgioia
    Studysummary In this retrospective study on pediatric craniospinal irradiation, researchers found that permanent radiation-induced alopecia occurred in 45.8% of patients, with higher radiation doses and treatment intensity being significant predictors, suggesting that defined dosimetric thresholds can support scalp-sparing planning.
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