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    Did you mean Homeobox Genes?
    Glossary Homeobox Genes

    regulatory genes controlling body plan and organ development

    Homeobox genes, often referred to as Hox genes, are a group of regulatory genes that play a crucial role in determining the body plan and the formation of tissues and organs during early embryonic development. They contain a specific DNA sequence called the homeobox, which encodes a protein domain (the homeodomain) that can bind to DNA and regulate the expression of other genes. This precise regulation ensures that body structures form in the correct locations.

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    Research 30 of 206

    1. Whole-genome resequencing to investigate the genetic diversity and the molecular basis underlying key economic traits in indigenous sheep breeds adapted to hypoxic environments Frontiers in Veterinary Science · 2025 · 1 citations
    2. <i>Hoxc13</i> mutant mice lack external hair Genes & Development · 1998 · 245 citations
    3. Gene expression patterns during palatal shelf fusion Journal of the American College of Surgeons · 2004
    4. Hox genes in development and beyond Development · 2023 · 83 citations
    5. Epidermal Dysplasia and Abnormal Hair Follicles in Transgenic Mice Overexpressing Homeobox Gene MSX-2 Journal of Investigative Dermatology · 1999 · 49 citations
    6. Hox in the Niche Controls Hairy-geneity Cell Stem Cell · 2018 · 4 citations
    7. PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis Stem Cell Research & Therapy · 2019 · 26 citations
    8. Seasonal Gene Expression Profile Responsible for Hair Follicle Development in Angora Goats 2023
    9. Structure and expression of the ovine Hoxc-13 gene Gene · 2003 · 12 citations
    10. Malignant Melanoma and Its Stromal Nonimmune Microecosystem Journal of Oncology · 2012 · 10 citations
    11. Gene expression profiling of intestinal regeneration in the sea cucumber BMC Genomics · 2009 · 106 citations
    12. Risk factors for prostate cancer: a case-control study investigating selected key exposures and their interactions with predisposition genes Jurnal Natural (Faculty of Mathematics and Natural Science, Syiah Kuala University) · 2010
    13. Seasonal Gene Expression Profile Responsible For Hair Follicle Development In Angora Goats Research Square (Research Square) · 2022 · 2 citations
    14. A preliminary study of differentially expressed genes in expanded skin and normal skin: implications for adult skin regeneration Archives of Dermatological Research · 2011 · 16 citations
    15. Hoxc13 polyglycine repeat gain-of-function drives mammalian integument evolution by altering targeted genes and interactions Research Square · 2026
    16. Maternal PPARγ protects nursing neonates by suppressing the production of inflammatory milk Genes & Development · 2007 · 102 citations
    17. Alopecia areata susceptibility variant identified by MHC risk haplotype sequencing reproduces symptomatic patched hair loss in mice bioRxiv (Cold Spring Harbor Laboratory) · 2018
    18. The inconsistent regulation of HOXC13 on different keratins and the regulation mechanism on HOXC13 in cashmere goat (Capra hircus) BMC Genomics · 2018 · 17 citations
    19. The HOXC13-controlled expression of early hair keratin genes in the human hair follicle does not involve TALE proteins MEIS and PREP as cofactors Archives of Dermatological Research · 2005 · 18 citations
    20. HOXC13 Is Involved in the Regulation of Human Hair Keratin Gene Expression Journal of Biological Chemistry · 2002 · 132 citations
    21. Hox in hair growth and development Die Naturwissenschaften · 2003 · 98 citations
    22. Molecular Genetic Characteristics of the Hoxc13 Gene and Association Analysis of Wool Traits International journal of molecular sciences · 2024
    23. The Nude Mutant Gene Foxn1 Is a HOXC13 Regulatory Target during Hair Follicle and Nail Differentiation 2010 · 68 citations
    24. Molecular characterization of HOXC8 gene and methylation status analysis of its exon 1 associated with the length of cashmere fiber in Liaoning cashmere goat Genetica · 2017 · 20 citations
    25. Network analysis reveals potential mechanisms that determine the cellular identity of keratinocytes and corneal epithelial cells through the Hox/Gtl2-Dio3 miRNA axis Frontiers in Cell and Developmental Biology · 2025
    26. Roles for Msx and Dlx homeoproteins in vertebrate development Gene · 2000 · 234 citations
    27. The mouse hairy ears mutation exhibits an extended growth (anagen) phase in hair follicles and altered <i>Hoxc</i> gene expression in the ears Veterinary Dermatology · 2008 · 10 citations
    28. Identification of differentially expressed genes affecting hair and cashmere growth in the Laiwu black goat by microarray Molecular Medicine Reports · 2016 · 4 citations
    29. Regulation of feather follicle development and Msx2 gene SNP degradation in Hungarian white goose BMC Genomics · 2022 · 1 citations
    30. Bioinformatic analysis of gene expression data reveals Src family protein tyrosine kinases as key players in androgenetic alopecia Frontiers in Medicine · 2023