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New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Old neuropharmacological drugs might be effective for treating inflammatory skin diseases.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Women with thyroid disease are more likely to experience female pattern hair loss, especially if they've had thyroid disease for a long time.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

The document concludes that more research is needed to understand how to treat muscle pain with drugs.

Androgens can both increase and decrease hair growth in different parts of the body.

Testosterone replacement is recommended for men with low testosterone levels and symptoms of hypogonadism.

A patient with a rare disease had a unique genetic mutation linked to their symptoms.

Genetic screening is crucial for accurately diagnosing APS-1 due to its varied symptoms.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

Thymic transplantation normalized some T-cells but not others, maintaining immune function.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.

The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

21-hydroxylase deficiency causes hormone imbalances leading to various symptoms, and diagnosis involves clinical and genetic tests.

Hormone imbalances from endocrine diseases can cause various skin conditions that help diagnose and treat these diseases early.

Omega-6 fats in certain cells boost male hormone production.

Eyelash loss can be a sign of thyroid problems.