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Obesity is linked to many gastrointestinal diseases and needs more research for treatment development.

Lifestyle changes like diet and exercise are key for treating overweight women with polycystic ovary syndrome.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.

DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.

Shorter CAG repeats in a specific gene may increase male hormone activity and symptoms like acne and excess hair in women with PCOS.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Women with PCOS have higher levels of certain blood clotting factors, suggesting a greater risk of cardiovascular issues.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Irregular menstrual cycles in teenagers are linked to a higher risk of polycystic ovary syndrome and metabolic syndrome.

Siblings with signs of virilization should be tested for non-classical congenital adrenal hyperplasia, which does not affect adult height but may impact fertility and well-being if untreated.

We need better ways to test and understand SARMs to make safer and more effective treatments.

Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.

Possible link between androgens and COVID-19 severity; more research needed.

People with polycystic ovary syndrome (PCOS) are more likely to have higher levels of depression and anxiety, but their personality traits are similar to those without PCOS.

Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.

Birth control pills increase certain receptor activities in female gerbil prostate glands and can lead to prostate changes.

Testosterone therapy can improve sexual function in women but long-term safety is unclear.

Pueraria mirifica extract may help treat benign prostatic hyperplasia.

Hormone therapy for breast cancer often leads to sexual issues like vaginal dryness and decreased libido.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.