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Hirsutism and acanthosis nigricans are reliable skin signs of PCOS and suggest the need for further tests for related health issues.

Many women experience sexual dysfunction, but few seek help, and better treatment and medical training are needed.

Vitamin D deficiency is common in women with PCOS and linked to some metabolic problems, but not the main cause of their metabolic issues.

Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.

CBG may help with various medical conditions but needs more human research to confirm safety and effectiveness.

Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.

Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Isotretinoin therapy for acne can cause many reversible side effects, mainly mild skin conditions, and patient understanding of these effects can improve treatment adherence.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Freeze-dried dexamethasone nanoparticles in a hydrogel are stable and effective for treating alopecia areata.

Manage women's cholesterol with diet, exercise, and careful treatment choices, especially during pregnancy, PCOS, and menopause.

Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.

Simvastatin may help manage symptoms in women with non-classic congenital adrenal hyperplasia by lowering cholesterol and certain hormone levels.

Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

Children with classic congenital adrenal hyperplasia have thicker heart fat and more heart and blood vessel risk factors, especially if their condition is not well-controlled.

The conclusion is that measuring how drugs partition into artificial sebum is important for predicting their delivery into hair and sebaceous follicles, and it provides better information than traditional methods.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

The document says PCOS is a common hormonal disorder in women, diagnosed by certain criteria, and managed with lifestyle changes and various medications.

Children with diabetes often have skin problems, which can be better managed with good blood sugar control.

The French Endocrine Society suggests diagnosing PCOS with two of three signs, recommends lifestyle changes and clomiphene for treatment, and calls for more research on certain treatments and tests.

Women with PCOS have similar levels of certain proteins compared to women without PCOS, and these proteins don't independently cause PCOS.

A postmenopausal woman's excessive hair growth and hair loss were due to a non-cancerous ovarian condition, treated successfully with surgery.

Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

Severe insulin resistance can be managed with medication, lifestyle changes, and treatment for related conditions.

Photodynamic Therapy is an effective treatment for mild to severe acne.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Future hair cosmetics will be safer and more effective.