December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Different types of inactive melanocyte stem cells exist with unique characteristics and potential to develop into other cells.
July 2023 in “Journal of Biomedical Science” Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair growth cycles need varied signals in space and time.
May 2018 in “The journal of immunology/The Journal of immunology” Mutations in the FOXN1 gene cause severe immune issues but don't affect hair and nails.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin heals with scars because only one type of fibroblast is used, not a mix.
211 citations,
May 2018 in “Trends in cell biology” Different types of skin cells play specific roles in development, healing, and cancer.
137 citations,
April 2015 in “Nature Reviews Molecular Cell Biology” Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.
129 citations,
May 2015 in “Cell Stem Cell” Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.
48 citations,
June 2020 in “Current Rheumatology Reports” Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.
43 citations,
August 2018 in “Cell Stem Cell” Hoxc genes control hair growth through Wnt signaling.
20 citations,
December 2012 in “Journal of molecular structure” The study found that thioglycolic acid breaks down hair bonds more consistently than l-cysteine, which is less damaging to hair.
20 citations,
January 2008 in “Reproductive Biomedicine Online” Sexual orientation does not affect the prevalence of PCOS or fertility rates in women undergoing artificial donor insemination.
14 citations,
December 2013 in “Molecules” Two compounds from Asiasarum heterotropoides roots show potential as lung cancer treatments without harming normal cells.
9 citations,
June 2000 in “Journal of The American Academy of Dermatology” Mutation in hairless gene may increase hair loss risk.
8 citations,
August 2007 in “Histopathology” Different growth patterns in thyroid tumors are influenced by where cell growth and death occur.
6 citations,
January 2013 in “The Journal of Dermatology” Researchers found a new genetic mutation causing a rare hair loss condition in the first Japanese child studied.
5 citations,
May 2014 in “Clinical and Experimental Dermatology” Mutations in the desmoplakin gene can cause hair problems and deadly heart disease.
2 citations,
June 2000 in “Journal of The American Academy of Dermatology” Mutation in hairless gene may increase hair loss risk.
2 citations,
October 2000 The investigation found no work-related causes for employee hair loss at Equifax Payment Services, and the environment was not hazardous.
1 citations,
August 2023 in “The Journal of Pathology” Different types of skin fibroblasts have unique roles in skin health and disease.
1 citations,
June 2022 in “Chinese medical journal/Chinese Medical Journal” Two new mutations in the CDH3 gene cause hair loss and vision problems in a young girl.
1 citations,
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” People with Hidradenitis Suppurativa have less diverse skin bacteria and different bacterial metabolism than healthy individuals.
1 citations,
January 1986 in “Journal of Steroid Biochemistry” Women with excessive hair growth or polycystic ovary disease may more often carry a gene variant for 21 hydroxylase deficiency.
Lupus is a complex disease that requires personalized treatment because it varies greatly between individuals.
April 2023 in “Journal of Investigative Dermatology” The specific skin disease variant p.(Arg2000Trp) in plectin can cause a wide range of symptoms, which should be considered when diagnosing patients.
March 2023 in “JAAD case reports” A new genetic change in the keratin 10 gene caused a skin condition called ichthyosis hystrix in a father and his daughter.
September 2019 in “Journal of Investigative Dermatology” Mouse skin fibroblasts vary in function and adaptability based on their environment.
May 2017 in “The journal of immunology/The Journal of immunology” Patients with certain FoxN1 gene mutations have severe immune issues but normal skin and hair.
September 2008 in “Fertility and Sterility” Exposure to fatty acids significantly increased androgen levels in female dogs, suggesting a link to conditions like insulin resistance and PCOS.
January 2004 in “Nederlands Tijdschrift voor Dermatologie & Venereologie”