1 citations
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October 2022 in “JCI insight” In this study, conditional deletion of BRD4 in OX40-expressing cells of mice led to alopecia, dermatitis, and loss of hair follicle stem cell function, revealing BRD4's role in skin inflammation and stem cell regulation.
1 citations
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February 2023 in “American Journal of Dermatopathology” Microscarring is found in both alopecia areata and pattern hair loss, suggesting a shared cause.
9 citations
,
February 2013 in “Plastic and Reconstructive Surgery” This article reviews options and principles for reconstructing defects of the scalp, skull, orbit, and maxilla, but reports no new clinical results.
In this case study, donor lymphocyte infusions effectively eradicated measurable residual disease in a patient with relapsed acute myeloid leukemia after hematopoietic cell transplantation, while side effects included the development of vitiligo and alopecia areata, likely due to chronic graft-versus-host disease.
50 citations
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May 1999 in “Journal of Reconstructive Microsurgery” This study concluded that microsurgical reconstruction is a reliable method to achieve stable coverage of large, complex scalp defects, although cancer control rates were poor.
19 citations
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August 2011 in “Facial Plastic Surgery Clinics of North America” This article discusses the use of hair transplantation as a reconstructive method to restore hair in various areas affected by defects, highlighting its advantages in providing natural-looking restoration.
1 citations
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August 2023 in “International Journal of Surgery Case Reports” In this study, free flaps, specifically the ALT-free tissue transfer, were found to be safe and reliable for reconstructing large scalp defects requiring both scalp and skull repairs, with consistent results observed in clinical applications.
This article provides an extensive overview of hair anatomy, physiology, pathology, and various medical and surgical treatments for alopecia but presents no new experimental findings.
256 citations
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October 2013 in “Nature Communications” This study demonstrates that bioengineered lacrimal gland germs can successfully develop and restore tear production and ocular surface protection in a mouse model with lacrimal gland dysfunction.
Miniflap hair restoration is a method to regrow hair.
May 2024 in “The Journal of Immunology” This study found that in mice, perforin-mediated cytolysis by CD8 T cells is not necessary for the autoimmune attack on hair follicles in alopecia areata, suggesting other mechanisms are responsible for disease progression.
2 citations
,
November 2020 in “Chirurgia” This article discusses the challenges and considerations in scalp reconstruction after tumor resection, trauma, alopecia, or irradiation, highlighting both functional and cosmetic goals without reporting new research findings.
1 citations
,
January 2019 in “Skin appendage disorders” This case report highlights that new onset non-scarring alopecia after allogeneic stem cell transplantation may indicate chronic graft-versus-host disease.
4 citations
,
May 2015 in “Indian Journal of Dermatology, Venereology and Leprology” Congenital triangular alopecia can occur outside the typical fronto-temporal region.
16 citations
,
June 2009 in “Dermatologic Surgery” This abstract does not contain research results or findings.
July 2026 in “Journal of King Saud University - Computer and Information Sciences” This study introduced a novel framework that significantly improves the accuracy of alopecia areata lesion segmentation in semi-supervised scenarios, outperforming existing methods and aiding in the disease's diagnosis, treatment, and staging, which can impact quality of life and mental well-being.
1 citations
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July 2007 in “Journal of Investigative Dermatology” The mutation causes hairless mice due to mislocalized and dysfunctional HR protein.
April 2023 in “Plastic Surgery” This study found that autologous fat grafting for facial asymmetry in progressive hemifacial atrophy and linear scleroderma showed similar outcomes regardless of whether performed during the active or stable phase of the disease, suggesting it may be a safe option in the active phase.
13 citations
,
June 2012 in “European journal of medical genetics” In this study, researchers observed monochorionic diamniotic twins with discordant clinical phenotypes, where one had high-grade trisomy 12p mosaicism in certain tissues, while the other showed confined mosaicism likely due to twin-to-twin transfusion.
January 2002 in “Agritrop (Cirad)” This study found that mutations in exon 3 of the hr gene are strongly associated with congenital hypotrichosis in Valle del Belice sheep, suggesting a potential genetic link to the disorder.
2 citations
,
July 2020 in “International journal of regenerative medicine” This study suggests that autologous fat transfer can significantly enhance hair growth in patients with scarring alopecia, offering more consistent and predictable results when combined with hair transplantation.
30 citations
,
August 2005 in “British journal of dermatology/British journal of dermatology, Supplement” This study identified a novel CDH3 mutation associated with sparse hair and pigmentary macular changes in two siblings with hypotrichosis but no visual symptoms.
February 2023 in “Cosmoderma” An infant with complete hair loss was diagnosed with a genetic disorder affecting hair growth.
3 citations
,
December 1987 in “The Journal of Dermatologic Surgery and Oncology” This article discusses reconstructive challenges following Mohs micrographic surgery on the forehead and reports no new clinical results, illustrating techniques applicable to this region.
January 2026 in “International Society of Hair Restoration Surgery” In this case study, a 35-year-old male with severe burn-related scalp injuries underwent successful reconstruction through tissue expansion, skin grafts, and multiple hair transplant sessions, resulting in satisfactory aesthetic and functional recovery.
9 citations
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January 2013 in “Journal of Cutaneous and Aesthetic Surgery” This case report observed complete repigmentation of a stable vitiligo patch with body hair transplantation in a 28-year-old man, with no recurrence after 3 months.
11 citations
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August 2010 in “Journal of Dermatology” This case report describes occipital hair transplantation for therapy-resistant alopecia areata in eyebrows, observing 80% hair re-growth two years post-surgery and suggesting surgical options may be useful for stable cases.
July 2003 in “Hair transplant forum international” This article mentions that the slot correction technique by Dr. Patrick Frechet has been a valuable tool in the author's 100% hair restoration surgery practice but does not provide new clinical results.
Mirror-image twins can have alopecia areata on opposite sides of their heads.
January 2011 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Bald men with male pattern baldness still have hair stem cells, but lack certain cells needed to grow hair.