86 citations,
December 2001 in “Experimental dermatology” Mutant mice help researchers understand hair growth and related genetic factors.
30 citations,
July 2010 in “Experimental Dermatology” Polyamines are important for hair growth, but more research is needed to understand their functions and treatment potential.
13 citations,
October 2010 in “Methods in molecular biology” Hair follicle culture helps study cell interactions and effects of substances on tissue growth.
2 citations,
December 2023 in “Royal Society of Chemistry eBooks” Hair is a complex organ, and understanding its detailed structure and growth phases is crucial for analyzing substances within it.
August 2016 in “Journal of Investigative Dermatology” The research found that certain microRNAs are important for human hair growth and health.
January 2012 in “Methods in pharmacology and toxicology” Hair follicle culture helps study hair growth but has limitations in modeling the full hair cycle.
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Advancements in hair biology include new treatments and tools for hair growth and alopecia.
11 citations,
October 2021 in “Frontiers in Cell and Developmental Biology” Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.
February 2024 in “International Journal of Molecular Sciences” Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.
January 2000 in “BioScience” The document concludes that understanding hair biology is key to treating hair disorders, with gene therapy showing potential as a future treatment.
103 citations,
November 2014 in “Journal of Cell Biology” MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
98 citations,
July 2014 in “Trends in Molecular Medicine” Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.
73 citations,
April 2019 in “Experimental Dermatology” The scalp's microorganisms significantly affect hair health and disease.
66 citations,
July 2015 in “Journal of Molecular Biology” The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.
1 citations,
November 2017 in “Journal of Investigative Dermatology” Platelet-rich plasma and microneedling could potentially help hair regrowth in alopecia areata patients, but more research is needed.
December 2012 in “Journal of Dermatological Science” Wnt/beta-catenin signaling in the skin helps fat cell development during hair growth and repair.
3 citations,
January 2012 in “Wageningen Academic Publishers eBooks” Hair health depends on various factors and hair loss can significantly affect a person's well-being; understanding hair biology is key for creating effective hair care treatments.
April 2018 in “Journal of Investigative Dermatology” Glycogen metabolism is important for energy and processes in human hair follicles, and hair follicles may produce glucose from lactate.
6 citations,
November 2010 in “Histochemistry and cell biology” The proteins transthyretin and megalin are more present in the growth phase of hair, suggesting they might affect hair health and growth.
June 2023 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” Impaired ABCA5 activity disrupts cholesterol balance in hair follicle cells, affecting hair growth.
159 citations,
July 2006 in “Endocrine Reviews” Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
41 citations,
September 2012 in “Cellular and Molecular Life Sciences” MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.
14 citations,
June 2017 in “Immunity” Special immune cells called Treg cells are important for maintaining and regenerating hair by activating a specific growth signal in hair stem cells.
September 2019 in “Journal of Investigative Dermatology” Researchers successfully used nude mice to study human hair growth, which could help with future hair research.
Melatonin helps regulate hair growth and may treat hair loss.
50 citations,
May 2004 in “Journal der Deutschen Dermatologischen Gesellschaft” Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.
May 2018 in “International journal of cell science & molecular biology” Early anti-aging hair treatments should focus on anti-inflammatory agents and promoting healthy hair growth cycles.
Retinoic acid affects hair growth and can cause hair loss.
236 citations,
July 2001 in “Trends in Molecular Medicine” Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.
146 citations,
May 2002 in “The American journal of pathology” Cathepsin L is essential for normal hair growth and development.