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    Glossary Hair Follicle Dystrophy

    condition where hair follicles are structurally abnormal or damaged

    Hair Follicle Dystrophy refers to a condition where the hair follicles are structurally abnormal or damaged, leading to impaired hair growth or hair loss. This can result from genetic factors, autoimmune disorders, or external damage such as trauma or harsh chemical treatments. The dystrophy disrupts the normal hair growth cycle, often causing thinning or patchy hair.

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    1. Hair follicle dystrophy in a litter of domestic cats resembling lanceolate hair mutant mice Veterinary dermatology · 2021 · 3 citations
    2. Modulation of Chemotherapy-Induced Human Hair Follicle Damage by 17-β Estradiol and Prednisolone: Potential Stimulators of Normal Hair Regrowth by “Dystrophic Catagen” Promotion? Journal of Investigative Dermatology · 2008 · 18 citations
    3. 259 Scalp hair follicle dermal sheath fibroblasts express genes associated with promotion of skin integrity/wound healing and prevention of autoimmune responses in Recessive Dystrophic Epidermolysis Bullosa Journal of Investigative Dermatology · 2024
    4. Annurca Apple Polyphenols Protect Murine Hair Follicles from Taxane Induced Dystrophy and Hijacks Polyunsaturated Fatty Acid Metabolism toward β-Oxidation Nutrients · 2018 · 19 citations
    5. 051 γδ T cells as novel players in alopecia areata pathobiology: Vδ1 + T lymphocytes may recognize “stressed” hair follicle keratinocytes, leading to IFNγ-dependent hair follicle dystrophy and immune privilege collapse Journal of Investigative Dermatology · 2016 · 1 citations
    6. 17‐beta estradiol and prednisolone as potential stimulators of hair re‐growth in chemotherapy‐induced human hair follicle damage via ‘dystrophic catagen’ promotion? Experimental Dermatology · 2008
    7. 441 Anti-melanoma gene signature in dermal sheath fibroblasts from scalp hair follicles in Recessive Dystrophic Epidermolysis Bullosa (RDEB) Journal of Investigative Dermatology · 2024
    8. Activation of mTORC1 Signaling is Required for Timely Hair Follicle Regeneration from Radiation Injury Radiation Research · 2017 · 12 citations
    9. Effect of N-acetylcysteine on hair follicle changes in mouse model of cyclophosphamide-induced alopecia: histological and biochemical study Histochemistry and cell biology · 2024
    10. LB789 Novel IFNγ aptamer TAGX-0003 protected hair follicles from immune privilege collapse and reversed Alopecia Areata like phenotype in humanized mouse model 2021
    11. Overexpression of Bcl-2 Protects from Ultraviolet B-Induced Apoptosis but Promotes Hair Follicle Regression and Chemotherapy-Induced Alopecia ˜The œAmerican journal of pathology · 2000 · 47 citations
    12. Effects of the selective TrkA agonist gambogic amide on pigmentation and growth of human hair follicles in vitro PLOS ONE · 2019 · 6 citations
    13. Angora Mouse Mutation: Altered Hair Cycle, Follicular Dystrophy, Phenotypic Maintenance of Skin Grafts, and Changes in Keratin Expression Veterinary Pathology · 1997 · 69 citations
    14. The Nude Mutant Gene Foxn1 Is a HOXC13 Regulatory Target during Hair Follicle and Nail Differentiation 2010 · 68 citations
    15. The role of P-cadherin in skin biology and skin pathology: lessons from the hair follicle 2015 · 15 citations
    16. The disrupted balance between hair follicles and sebaceous glands in<i>Hoxc13</i>‐ablated rabbits ˜The œFASEB journal · 2018 · 18 citations
    17. 1400 Low-intensity ultrasound protects human scalp hair follicles from taxane-induced toxicity 2023
    18. A Guide to Assessing Damage Response Pathways of the Hair Follicle: Lessons From Cyclophosphamide-Induced Alopecia in Mice Journal of Investigative Dermatology · 2005 · 106 citations
    19. Chemotherapy Targets the Hair-Follicle Vascular Network but Not the Stem Cells Journal of Investigative Dermatology · 2006 · 45 citations
    20. The Transient Role for Calcium and Vitamin D during the Developmental Hair Follicle Cycle Journal of Investigative Dermatology · 2016 · 18 citations
    21. Histologic and Cell Kinetic Studies of Hair Loss and Subsequent Recovery Process of Human Scalp Hair Follicles Grafted onto Severe Combined Immunodeficient Mice Journal of Investigative Dermatology · 2000 · 31 citations
    22. Histologic Study of the Regeneration Process of Human Hair Follicles Grafted onto SCID Mice after Bulb Amputation Journal of Investigative Dermatology Symposium Proceedings · 2001 · 19 citations
    23. Structural changes in hair follicles and sebaceous glands of hairless mice following exposure to sulfur mustard Experimental and Molecular Pathology · 2014 · 14 citations
    24. An Experimental Study of Morphofunctional Features of Hair Follicles Early Response in Cyclophosphamide-Induced Alopecia Journal of Anatomy and Histopathology · 2024
    25. Mimicking Hair Disorders by Genetic Manipulation of Organ-Cultured Human Hair Follicles Journal of Investigative Dermatology · 2012 · 5 citations
    26. Alopecia Areata in C3H/HeJ Mice Involves Leukocyte-mediated Root Sheath Disruption in Advance of Overt Hair Loss Veterinary pathology · 2003 · 37 citations
    27. MOUSE MODELS FOR THE STUDY OF HUMAN HAIR LOSS Dermatologic Clinics · 1996 · 36 citations
    28. Parathyroid hormone linked to a collagen binding domain promotes hair growth in a mouse model of chemotherapy-induced alopecia in a dose-dependent manner Anti-Cancer Drugs · 2014 · 8 citations
    29. FGF signaling for hair cycle resting phase alleviates radiation alopecia Journal of Dermatological Science · 2016 · 1 citations
    30. Mimicking Senescence Factors to Characterize the Mechanisms Responsible for Hair Regression and Hair Loss: An In Vitro Study Organoids · 2025