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    Glossary Dermal Papillae

    small skin projections crucial for hair growth and nutrient supply

    Dermal papillae are small, nipple-like extensions of the dermis (the inner layer of the skin) that project into the epidermis (the outer layer of the skin). In the context of hair, they are located at the base of hair follicles and play a crucial role in hair growth by supplying nutrients and signaling molecules to the hair matrix cells, which are responsible for producing hair.

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    1. Hair matrix germinative epidermal cells confer follicle-inducing capabilities on dermal sheath and high passage papilla cells Development · 1996 · 61 citations
    2. TGF‐β<sub>2</sub> is specifically expressed in human dermal papilla cells and modulates hair folliculogenesis Journal of Cellular and Molecular Medicine · 2009 · 43 citations
    3. Maintaining Hair Inductivity in Human Dermal Papilla Cells: A Review of Effective Methods Skin Pharmacology and Physiology · 2020 · 35 citations
    4. Identification of a new plant extract for androgenic alopecia treatment using a non-radioactive human hair dermal papilla cell-based assay BMC Complementary and Alternative Medicine · 2015 · 17 citations
    5. Titrated extract of<i>Centella asiatica</i>increases hair inductive property through inhibition of STAT signaling pathway in three-dimensional spheroid cultured human dermal papilla cells Bioscience, Biotechnology, and Biochemistry · 2017 · 13 citations
    6. Identification of androgen-regulated genes in SV40-transformed human hair dermal papilla cells Journal of dermatological science · 2003 · 12 citations
    7. Implication of microRNA regulation in para-phenylenediamine-induced cell death and senescence in normal human hair dermal papilla cells Molecular Medicine Reports · 2015 · 8 citations
    8. In Vitro hair growth and hair tanning activities of mangosteen pericarp extract on hair dermal papilla cells Journal of Herbal Medicine · 2022 · 6 citations
    9. <i>Lagerstroemia indica</i> extract regulates human hair dermal papilla cell growth and degeneration via modulation of β‐catenin, Stat6, and TGF‐β signaling pathway Journal of Cosmetic Dermatology · 2022 · 6 citations
    10. Effects of Adipose-Derived Stem Cells and Platelet-Rich Plasma Exosomes on The Inductivity of Hair Dermal Papilla Cells. PubMed · 2021 · 5 citations
    11. Effect of ethanol extract of plant mixture on hair regeneration in human dermal papilla cells and C57BL/6J mice Journal of Medicinal Plants Research · 2015 · 4 citations
    12. Effect of a Serenoa repens extract on human primary hair dermal papilla cells isolated from male and female donors Planta Medica · 2026
    13. Hair Dermal papilla maintain its hair inducing characteristics via autocrine exosomal miR-23a-3p 2025
    14. Hair growth–promoting effects of Enz_MoriL on human dermal papilla cells through modulation of the Wnt/β-Catenin and JAK-STAT signaling pathways Archives of dermatological research · 2024
    15. Gynostemma pentaphyllum Hydrodistillate and Its Major Component Damulin B Promote Hair Growth-Inducing Properties In Vivo and In Vitro via the Wnt/β-Catenin Pathway in Dermal Papilla Cells Nutrients · 2024
    16. Hair growth and hair tanning activities of mangosteen pericarp water extract on hair dermal papilla cells 2016
    17. Hair multiplication with dermal papilla like tissue containing human dermal papilla cells Biotechnology and Bioprocess Engineering · 2014
    18. Cortexolone 17a-propionate: A new antiandrogen acting on hair dermal papilla cells for the treatment of androgenic alopecia Journal of The American Academy of Dermatology · 2014
    19. Hair dermal papilla cell metabolism is influenced by minoxidil Fundamental & Clinical Pharmacology · 1997
    20. The Dermal Papilla and Hair Follicle Regeneration: Engineering Strategies to Improve Dermal Papilla Inductivity Stem cell biology and regenerative medicine · 2022
    21. The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair Follicle Cold Spring Harbor Perspectives in Medicine · 2014 · 149 citations
    22. Scalable production of controllable dermal papilla spheroids on PVA surfaces and the effects of spheroid size on hair follicle regeneration Biomaterials · 2012 · 78 citations
    23. Analysis of Dermal Papilla Cell Interactome Using STRING Database to Profile the ex Vivo Hair Growth Inhibition Effect of a Vinca Alkaloid Drug, Colchicine International Journal of Molecular Sciences · 2015 · 23 citations
    24. Sheep vibrissa dermal papillae induce hair follicle formation in heterotypic skin equivalents British Journal of Dermatology · 1994 · 21 citations
    25. THE USE OF DERMAL PAPILLA CELLS IN STUDIES OF NORMAL AND ABNORMAL HAIR FOLLICLE BIOLOGY Dermatologic Clinics · 1996 · 19 citations
    26. Nature-derived lignan compound VB-1 exerts hair growth-promoting effects by augmenting Wnt/β-catenin signaling in human dermal papilla cells PeerJ · 2018 · 17 citations
    27. Osteopontin Gene is Expressed in the Dermal Papilla of Pelage Follicles in a Hair-Cycle-Dependent Manner Journal of Investigative Dermatology · 2001 · 17 citations
    28. Hair Growth Promoting Effect of <i>Hottuynia cordata</i> Extract in Cultured Human Hair Follicle Dermal Papilla Cells Biological & Pharmaceutical Bulletin · 2019 · 16 citations
    29. Polygonum multiflorum extract support hair growth by elongating anagen phase and abrogating the effect of androgen in cultured human dermal papilla cells BMC complementary medicine and therapies · 2020 · 15 citations
    30. Acute Stress-Induced Changes in Follicular Dermal Papilla Cells and Mobilization of Mast Cells: Implications for Hair Growth Annals of Dermatology · 2016 · 13 citations