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Topical contact sensitizers can treat certain skin conditions but are rarely used in the U.K.

New JAK inhibitor drugs show promise for treating skin diseases but need more research on safety and effectiveness.

Alopecia areata leads to significantly higher healthcare costs due to more doctor visits and prescriptions.

Researchers found 24 genes that change significantly and affect cashmere growth in goats; this could help increase cashmere production.

Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

New treatments for male hypogonadism are effective and should be personalized.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Lamins are vital for cell survival, organ development, and preventing premature aging.

Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.

Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.

Stress activates a special function of the Vitamin D receptor with the help of c-Jun, which can also prevent cell death.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

Many skin patients also have mental health issues, and doctors should treat both together.

The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

Delayed ejaculation is a complex issue caused by psychological, biological, and lifestyle factors, requiring a holistic treatment approach.

Liposomes show promise in cancer treatment by delivering drugs with less toxicity and improved effectiveness.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

The study concludes that certain domains in Clostridium histolyticum enzymes are structurally unique, bind calcium to become more stable, and play distinct roles in breaking down collagen, with potential applications in medicine and drug delivery.

Finasteride exposure harms tadpole reproduction and hormone balance.