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    Did you mean Growth Factor Signaling?
    Glossary Growth Factor Signaling

    process where proteins trigger cellular growth and repair

    Growth Factor Signaling refers to the process by which certain proteins, known as growth factors, bind to specific receptors on the surface of cells, triggering a cascade of biochemical reactions inside the cell. This signaling pathway is crucial for regulating various cellular activities, including growth, division, and differentiation, and plays a significant role in tissue repair and development. For example, in the context of hair growth, specific growth factors can stimulate hair follicle cells to enter the growth phase, promoting hair regeneration.

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    1. Hair-Growth-Promoting Effects of the Fish Collagen Peptide in Human Dermal Papilla Cells and C57BL/6 Mice Modulating Wnt/β-Catenin and BMP Signaling Pathways International Journal of Molecular Sciences · 2022
    2. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth-Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019 · 136 citations
    3. BMP signaling in the control of skin development and hair follicle growth Differentiation · 2004 · 165 citations
    4. Millet seed oil activates β–catenin signaling and promotes hair growth Frontiers in Pharmacology · 2023 · 1 citations
    5. Recombinant Type XVII Collagen Promotes Hair Growth by Activating the Wnt/β-Catenin and SHH/GLI Signaling Pathways Cosmetics · 2025
    6. Platelet-Rich Plasma Contains High Concentrations of DKK1, A Potent Inhibitor of Wnt Signaling that Limits Bone Regeneration and Hair Growth Journal of orthopedics & bone disorders · 2023
    7. 562 Neuroendocrinology of human scalp hair follicles: Growth hormone-releasing hormone (GHRH) stimulates hair growth and controls a fully functional intrafollicular hypothalamic-pituitary-somatotropic (HPS) signaling axis Journal of Investigative Dermatology · 2022
    8. Mathematical Modeling and Inference of Epidermal Growth Factor-Induced Mitogen-Activated Protein Kinase Cell Signaling Pathways International Journal of Molecular Sciences · 2024 · 3 citations
    9. Hairless triggers reactivation of hair growth by promoting Wnt signaling Proceedings of the National Academy of Sciences of the United States of America · 2005 · 137 citations
    10. Epidermal growth factor promotes proliferation of dermal papilla cells via Notch signaling pathway Biochimie · 2016 · 36 citations
    11. Fibroblast bioelectric signaling drives hair growth Cell · 2025 · 3 citations
    12. Astragalus membranaceus and Cinnamomum cassia Stimulate the Hair Follicle Differentiation-Related Growth Factor by the Wnt/β-Catenin Signaling Pathway Current Issues in Molecular Biology · 2023
    13. WNT Signaling in the Control of Hair Growth and Structure Developmental biology · 1999 · 271 citations
    14. Modulation of Hair Growth with Small Molecule Agonists of the Hedgehog Signaling Pathway Journal of Investigative Dermatology · 2005 · 113 citations
    15. Epidermal Growth Factor Induces Proliferation of Hair Follicle-Derived Mesenchymal Stem Cells Through Epidermal Growth Factor Receptor-Mediated Activation of ERK and AKT Signaling Pathways Associated with Upregulation of Cyclin D1 and Downregulation of p16 Stem Cells and Development · 2016 · 83 citations
    16. Prolactin Signaling Influences the Timing Mechanism of the Hair Follicle: Analysis of Hair Growth Cycles in Prolactin Receptor Knockout Mice* Endocrinology · 2001 · 73 citations
    17. Keratinocyte Growth Inhibition through the Modification of Wnt Signaling by Androgen in Balding Dermal Papilla Cells 2009 · 70 citations
    18. Hair growth-promoting effect of Aconiti Ciliare Tuber extract mediated by the activation of Wnt/β-catenin signaling Life Sciences · 2012 · 45 citations
    19. Epidermal Growth Factor Promotes Proliferation and Migration of Follicular Outer Root Sheath Cells via Wnt/β-Catenin Signaling Cellular physiology and biochemistry · 2016 · 43 citations
    20. 3-Deoxysappanchalcone Promotes Proliferation of Human Hair Follicle Dermal Papilla Cells and Hair Growth in C57BL/6 Mice by Modulating WNT/β-Catenin and STAT Signaling Biomolecules & Therapeutics · 2016 · 26 citations
    21. Exosomal miRNA-181a-5p from the cells of the hair follicle dermal papilla promotes the hair follicle growth and development via the Wnt/β-catenin signaling pathway International journal of biological macromolecules · 2022 · 25 citations
    22. Morroniside regulates hair growth and cycle transition via activation of the Wnt/β-catenin signaling pathway Scientific Reports · 2018 · 25 citations
    23. Prolactin Signaling Influences the Timing Mechanism of the Hair Follicle: Analysis of Hair Growth Cycles in Prolactin Receptor Knockout Mice Endocrinology · 2001 · 14 citations
    24. Decoction and Fermentation of Selected Medicinal Herbs Promote Hair Regrowth by Inducing Hair Follicle Growth in Conjunction with Wnts Signaling Evidence-based Complementary and Alternative Medicine · 2016 · 6 citations
    25. Melatonin increases growth properties in human dermal papilla spheroids by activating AKT/GSK3β/β-Catenin signaling pathway PeerJ · 2022 · 4 citations
    26. Ginsenoside Rg4 Enhances the Inductive Effects of Human Dermal Papilla Spheres on Hair Growth Via the AKT/GSK-3β/β-Catenin Signaling Pathway Journal of Microbiology and Biotechnology · 2021 · 4 citations
    27. The Philippines stingless bee propolis promotes hair growth through activation of Wnt/β-catenin signaling pathway Jikken Dobutsu · 2022 · 2 citations
    28. PD-L1 vNAR promotes hair growth by modulating hair shaft elongation through activating the leptin-STAT3 signaling Cell Communication and Signaling · 2026
    29. Application of a novel ingredient Blend promotes hair growth by modulating Wnt/β‐catenin signaling, DP inductivity, and boosting elastin expression in healthy human scalp hair follicles ex vivo Journal of Cosmetic Dermatology · 2026
    30. Blue honeysuckle (Lonicera caerulea L.) fruit extract promotes hair growth via β-catenin signaling pathway Food Science and Biotechnology · 2026