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The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Minoxidil and finasteride treat hair loss; more research needed for other options.

Belimumab reduces disease activity, steroid use, and flares in lupus patients.

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Epidermal Growth Factor helps hair follicle cells grow and move by activating a specific cell signaling pathway.

TGF-β2 plays a key role in human hair growth and development.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Hair follicles on the scalp interact with and respond to the nervous system, influencing their own behavior and growth.

Indigenous herbal medicines in the Indian subcontinent have potential for drug development but need more research and standardization.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

Minoxidil can reduce functions related to androgen receptors.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

The document concludes that diagnosing PCOS in teenagers is difficult and should focus on specific hormone levels and menstrual irregularities, while also considering treatment for symptoms and related health issues.