research Topical Use of Systemic Drugs in Dermatology: A Comprehensive Review
Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.
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research Skin Toxicity of Anti-Cancer Therapy
Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.
research A Rational Approach to the Treatment of Vitiligo and Other Hypomelanoses
Tailor treatments for vitiligo to patient needs for best results.
research Atrichia With Papular Lesions Resulting From a Novel Insertion Mutation in the Human Hairless Gene
Researchers found a new mutation causing total hair loss from birth.
research The Modern Management of Hirsutism
Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.
research Medical Management of Male Pattern Hair Loss
Minoxidil and finasteride can slow or halt hair loss, but may have side effects.
research Androgenic and Anti-Androgenic Effects of Progesterone Derivatives with Different Halogens as Substituents at the C-6 Position
Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.
research The Use of Dermal Papilla Cells in Studies of Normal and Abnormal Hair Follicle Biology
Dermal papilla cells are key for hair growth and could help us understand and treat hair loss.
research Where Have the Periods Gone? The Evaluation and Management of Functional Hypothalamic Amenorrhea
The document concludes that Functional Hypothalamic Amenorrhea should be carefully diagnosed and managed to prevent health complications, using lifestyle changes and specific medications.
research Molecular Genetics of Keratinization Disorders: What's New About Ichthyosis
Over 67 genes linked to ichthyosis help improve diagnosis and treatment.
research Infertility and Teratogenicity After Paternal Exposure to Systemic Dermatologic Medications: A Systematic Review
Some skin medications can harm male fertility, but they don't seem to cause birth defects from father's exposure.
research Evaluation of the Efficacy of Transdermal Drug Delivery of Calcipotriol Plus Betamethasone Versus Tacrolimus in the Treatment of Vitiligo
Calcipotriol plus betamethasone with microneedling works better than tacrolimus for treating vitiligo.
research Telogen Effluvium: Is There a Need for a New Classification
The paper suggests improving diagnosis and treatment of telogen effluvium but does not recommend a new classification system.
research Dietary Vitamin A Regulates Wingless-Related MMTV Integration Site Signaling to Alter the Hair Cycle
Eating vitamin A affects hair growth and health by changing cell signals in mice.
research The Utility of Metformin Therapy in Reproductive-Aged Women with Polycystic Ovary Syndrome
Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.
research Dermatological Problems of Puberty
Puberty often causes skin issues like acne and excessive sweating, and treatments require patience as results may vary.
research Primary Cicatricial Alopecias
Early diagnosis and aggressive treatment are key for managing rare scalp disorders that cause permanent hair loss.
research Exposure of Xenopus Laevis Tadpoles to Finasteride, an Inhibitor of 5-Alpha Reductase Activity, Impairs Spermatogenesis and Alters Hypophyseal Feedback Mechanisms
Finasteride exposure harms tadpole reproduction and hormone balance.
research Effects of the Chronic Use of Finasteride on Testicular Weight and Spermatogenesis in Wistar Rats
Finasteride doesn't change rat testicle weight or sperm production.
research Adverse Cutaneous Reactions to Chemotherapeutic Agents and Cytokine Therapy
Chemotherapy and cytokine therapy can cause various skin reactions, including hair loss and hypersensitivity.
research Dermatologic Diseases and Problems of Women Throughout the Life Cycle
Women experience various skin issues at different life stages, requiring careful treatment and awareness.
research Cyclosporine Therapy for Bullous Erythema Multiforme
Cyclosporine cleared a woman's resistant skin condition quickly and kept it away for over a year.
research The Probable Destructive Mechanisms Behind COVID-19 on Male Reproductive System and Fertility
COVID-19 may harm male fertility and damage the reproductive system.
research Considerations in Genetic Counseling of Transgender Patients: Cultural Competencies and Altered Disease Risk Profiles
Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.
research Medical Options for Care of Gender Diverse and Transgender Youth
Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.
research Evaluation and Treatment of Gender Dysphoria to Prepare for Gender Confirmation Surgery
The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.
research Synthesis and Biological Evaluation of Novel Unsaturated Carboxysteroids as Human 5α-Reductase Inhibitors: A Legitimate Approach
New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.
research Combination Therapy With Finasteride and Low-Dose Dutasteride in the Treatment of Androgenetic Alopecia
Finasteride and low-dose dutasteride combo improves hair growth and reduces hair loss with no major side effects.
research A Review on Steroidal 5α-Reductase Inhibitors for Treatment of Benign Prostatic Hyperplasia
New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.
research Porokeratotic Eccrine Duct and Hair Follicle Nevus (PEHFN) Associated with Keratitis-Ichthyosis-Deafness (KID) Syndrome
A 15-year-old with KID syndrome developed a rare skin condition called PEHFN.