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Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

Wound healing insights can improve regenerative medicine.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.

Caucasian women's hair appears thickest in their 20s, with perceived thinning after mid-30s due to both decreasing density and diameter.

RANK-RANKL signaling is essential for hair growth and skin health.

High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Prostaglandin D₂ might be targeted for new male pattern baldness treatments.

Improving the environment and cell interactions is key for creating human hair in the lab.

Vitamin D receptor is crucial for starting hair growth after birth.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

miR-22, a type of microRNA, controls hair growth and its overproduction can cause hair loss, while its absence can speed up hair growth.

Asian hair loss differs from Europeans; consider individual needs and psychological well-being for treatment.

Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.

The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.

Hair analysis for drugs needs a better understanding of how drugs enter hair, considering factors like hair structure and pigmentation.

Insulin resistance is significantly linked to a higher risk of depression in women with PCOS.