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Genetic screening for NUDT15 polymorphisms is crucial for patients taking azathioprine, especially in Asians.

Understanding skin structure and development helps diagnose and treat skin disorders.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

Early treatment of PCOS in teens is crucial to prevent long-term health issues like diabetes and heart disease.

Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.

Genetic variants can affect valproic acid's effectiveness, side effects, and levels in epilepsy treatment.

Rare genetic variants in five specific genes are linked to male-pattern hair loss but only account for a small part of the risk.

Early diagnosis and personalized treatments are crucial for better hair loss management.

Studying rare genetic disorders can help us understand and treat common diseases better.

Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.

Acne vulgaris is a common skin condition that can cause low self-esteem and depression, and early treatment is important to prevent scarring.

Female hair loss is often hereditary and can be treated with medication, hair transplants, and lasers.

Early signs of PCOS in girls, like irregular periods and polycystic ovaries, suggest a need for early diagnosis and intervention to prevent further health issues.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

Monilethrix is a rare genetic hair disorder that's hard to treat.

Certain genetic variations in the RAB5B gene are linked to a higher risk of polycystic ovary syndrome in Chinese Han women.

Certain genetic mutations can lower bad cholesterol and reduce heart disease risk, leading to effective cholesterol-lowering drugs.

Early genetic testing and JAK inhibitors can help treat systemic inflammation in SAVI patients.

Longer CAG and GGN repeats increase alopecia risk, but no significant link to post-finasteride syndrome found.

People with the same genetic mutation for Woodhouse-Sakati syndrome can have different symptoms.

Alopecia areata involves complex immune and genetic factors, with potential treatment targets identified, but more research is needed.

Pangolins have lost some skin-related genes, but kept others, leading to their unique scales and skin features.

Pangolins have lost some skin-related genes, but kept others, showing complex skin evolution.

Tandem repeats significantly influence hair color, especially darker shades, across different ancestries.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Vitiligo is linked to autoimmune diseases and hearing issues, so hearing tests are recommended for patients.

Thiopurines help treat IBD but require genetic testing to avoid side effects.

No link found between specific genes and female pattern hair loss.

The document concludes that over 500 genes are linked to hair disorders and this knowledge is important for creating new treatments.

Birt–Hogg–Dubé syndrome is a rare genetic condition causing skin lesions, lung cysts, and a higher chance of kidney cancer.