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The Role of Candidate Pharmacogenetic Variants in Determining Valproic Acid Efficacy, Toxicity, and Concentrations in Patients with Epilepsy

research The Role of Candidate Pharmacogenetic Variants in Determining Valproic Acid Efficacy, Toxicity, and Concentrations in Patients with Epilepsy

October 2024 in “Frontiers in Pharmacology”

Genetic variants can affect valproic acid's effectiveness, side effects, and levels in epilepsy treatment.

research Insulin Resistance Syndrome: The Sensitive IRS

January 2018

Insulin resistance is linked to many health problems and is influenced by diet, genetics, and other factors.

A Pharmacogenetic Survey of Androgen Receptor (CAG)N and (GGN)N Polymorphisms in Patients Experiencing Long-Term Side Effects After Finasteride Discontinuation

research A Pharmacogenetic Survey of Androgen Receptor (CAG)N and (GGN)N Polymorphisms in Patients Experiencing Long-Term Side Effects After Finasteride Discontinuation

16 citations, December 2014 in “International Journal of Biological Markers”

Longer CAG and GGN repeats increase alopecia risk, but no significant link to post-finasteride syndrome found.

Lack of Concordance and Linkage Disequilibrium Among Brothers for Androgenetic Alopecia and CAG/GGC Haplotypes of the Androgen Receptor Gene in Mexican Families

research Lack of Concordance and Linkage Disequilibrium Among Brothers for Androgenetic Alopecia and CAG/GGC Haplotypes of the Androgen Receptor Gene in Mexican Families

2 citations, July 2015 in “Journal of Cosmetic Dermatology”

No clear link between specific gene and hair loss in Mexican brothers.

research The Role of Rare Variants in Male-Pattern Hair Loss: Analysis of Whole Exome Sequencing Data in the UK Biobank

November 2022 in “Journal of Investigative Dermatology”

Rare genetic variants in 125 genes are linked to male-pattern hair loss.

research The Role of CYP19A1 and ESR2 Gene Polymorphisms in Female Androgenetic Alopecia in the Polish Population

October 2021 in “Postepy Dermatologii I Alergologii”

No significant link was found between the studied genes and female hair loss in the Polish population.

research Expanding Phenotype of Hereditary Fibrosing Poikiloderma with Tendon Contractures, Myopathy, and Pulmonary Fibrosis Caused by FAM111B Mutations: Report of an Additional Family Raising the Question of Cancer Predisposition and a Short Review of Early-Onset Poikiloderma

23 citations, March 2017 in “JAAD case reports”

The document suggests a possible link between FAM111B gene mutations and increased cancer risk, particularly pancreatic cancer.

research Male-Pattern Baldness and Its Association with Coronary Heart Disease

September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

Male-pattern baldness has a weak link to heart disease and some related health conditions.

Incidence of Adverse Cutaneous Drug Reactions in a Mexican Sample: An Exploratory Study on Their Association to Tumor Necrosis Factor Alpha TNF2 Allele

research Incidence of Adverse Cutaneous Drug Reactions in a Mexican Sample: An Exploratory Study on Their Association to Tumor Necrosis Factor Alpha TNF2 Allele

6 citations, March 2009 in “Journal of the European Academy of Dermatology and Venereology”

Mexican patients had a lower incidence of skin reactions to drugs and no significant link between these reactions and the TNF2 gene variant.

research Multiple Basal Cell Carcinomas in a Patient with Myotonic Dystrophy Type 1

3 citations, March 2019 in “Case Reports”

A man with myotonic dystrophy type 1 had 28 skin cancers, suggesting a link between the disease and skin cancer, emphasizing the need for sun protection and regular skin checks.

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