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The conclusion is that there's a link between high testosterone levels, insulin resistance, and certain skin conditions, regardless of obesity.

Managing metabolic syndrome needs both lifestyle changes and medical treatments.

Polycystic ovary syndrome affects about 6-10% of women, with varying symptoms and the need for standardized global definitions.

Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Low-level laser therapy, now called photobiomodulation, is recognized for its broad medical applications and scientific backing.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Skin fat helps with body temperature control and has other active roles in health.

Eating fewer calories, less sugar and refined carbs, and more low-glycemic and omega-3 rich foods can help manage PCOS symptoms.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Certain medications including flutamide, spironolactone, and others effectively reduce excessive hair growth in women, especially when combined with lifestyle changes.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Women with PCOS have similar levels of certain proteins compared to women without PCOS, and these proteins don't independently cause PCOS.

A male with aromatase deficiency improved bone health with estradiol treatment.

Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.

Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.

People who carry the 21-Hydroxylase Deficiency gene are not more likely to have excessive male hormone levels.

Girls with PCOS during adolescence have a higher risk of developing type 2 diabetes, and early treatment can help manage this risk.

PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.

Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.

The document concludes that health care providers should offer culturally competent care and more research is needed to improve health outcomes for transgender individuals.

Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.

FAI values above 6.4 may suggest high androgen levels and increased metabolic risks in Chinese women of reproductive age.

Many women with hard-to-treat acne also have PCOS.

Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.

Cosmetic surgery is more popular and cost-effective, but outcomes depend on the surgeon's skill and all procedures have potential complications.

Alopecia areata may be linked to imbalanced gut bacteria.

Early diagnosis and treatment of PCOS in young people is important to prevent long-term health problems.