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    Glossary Genes

    segments of DNA that encode instructions for protein synthesis

    Genes are segments of DNA that act as instructions for building and maintaining the body's cells and tissues. They determine inherited traits, such as eye color or susceptibility to certain diseases, by encoding for specific proteins that perform various functions in the body.

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    Research 30 of 1000+

    1. Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria PLOS Genetics · 2018 · 308 citations
    2. Polymorphism of the Androgen Receptor Gene is Associated with Male Pattern Baldness Journal of Investigative Dermatology · 2001 · 299 citations
    3. Genes for intermediate filament proteins and the draft sequence of the human genome Journal of Cell Science · 2001 · 287 citations
    4. Genetic, hormonal and metabolic aspects of PCOS: an update Reproductive Biology and Endocrinology · 2016 · 258 citations
    5. Fetal Programming of Polycystic Ovary Syndrome by Androgen Excess: Evidence from Experimental, Clinical, and Genetic Association Studies The Journal of Clinical Endocrinology and Metabolism · 2006 · 253 citations
    6. The role of keratin proteins and their genes in the growth, structure and properties of hair Birkhäuser Basel eBooks · 1997 · 228 citations
    7. Selective Modulation of Hedgehog/GLI Target Gene Expression by Epidermal Growth Factor Signaling in Human Keratinocytes Molecular and Cellular Biology · 2006 · 226 citations
    8. Conditional Gene Expression in the Epidermis of Transgenic Mice Using the Tetracycline-Regulated Transactivators tTA and rTA Linked to the Keratin 5 Promoter Journal of Investigative Dermatology · 2000 · 215 citations
    9. Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia American Journal of Human Genetics · 2005 · 195 citations
    10. Human Hair Growth Deficiency Is Linked to a Genetic Defect in the Phospholipase Gene <i>LIPH</i> Science · 2006 · 194 citations
    11. Genetic Basis of Male Pattern Baldness Journal of Investigative Dermatology · 2003 · 191 citations
    12. Generic Development of Topical Dermatologic Products: Formulation Development, Process Development, and Testing of Topical Dermatologic Products The AAPS Journal · 2012 · 188 citations
    13. Keratin gene mutations in disorders of human skin and its appendages Archives of Biochemistry and Biophysics · 2010 · 185 citations
    14. Genetics of polycystic ovary syndrome: searching for the way out of the labyrinth Human Reproduction Update · 2005 · 179 citations
    15. The <i>hairless</i> gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor Genes & Development · 2001 · 178 citations
    16. Genetic Analysis of Male Pattern Baldness and the 5α-Reductase Genes Journal of Investigative Dermatology · 1998 · 169 citations
    17. Health-related quality of life in women with polycystic ovary syndrome: A comparison with the general population using the Polycystic Ovary Syndrome Questionnaire (PCOSQ) and the Short Form-36 (SF-36) Gynecological Endocrinology · 2006 · 167 citations
    18. Genetic Variation at the MC1R Locus and the Time since Loss of Human Body Hair Current anthropology · 2004 · 152 citations
    19. Genetic Disorders and Defects in Vitamin D Action Endocrinology and metabolism clinics of North America · 2010 · 151 citations
    20. Generalized Pustular Psoriasis Archives of Dermatology · 1991 · 143 citations
    21. Atrichia Caused by Mutations in the Vitamin D Receptor Gene is a Phenocopy of Generalized Atrichia Caused by Mutations in the Hairless Gene 2001 · 139 citations
    22. Genetic prediction of male pattern baldness PLoS Genetics · 2017 · 133 citations
    23. Genetic architecture of mouse skin inflammation and tumour susceptibility Nature · 2009 · 133 citations
    24. Vestibular Hair Cell Regeneration and Restoration of Balance Function Induced by Math1 Gene Transfer Otology & Neurotology · 2007 · 129 citations
    25. Genetically Altered Expression of Spermidine/Spermine N1-Acetyltransferase Affects Fat Metabolism in Mice via Acetyl-CoA Journal of Biological Chemistry · 2006 · 128 citations
    26. Molecular evolution of the keratin associated protein gene family in mammals, role in the evolution of mammalian hair BMC Evolutionary Biology · 2008 · 119 citations
    27. Gene Array Profiling and Immunomodulation Studies Define a Cell-Mediated Immune Response Underlying the Pathogenesis of Alopecia Areata in a Mouse Model and Humans Journal of Investigative Dermatology · 2002 · 114 citations
    28. Integument pattern formation involves genetic and epigenetic controls: feather arrays simulated by digital hormone models. ˜The œInternational journal of developmental biology · 2004 · 112 citations
    29. Genetic basis of skin appendage development Seminars in cell & developmental biology · 2007 · 111 citations
    30. Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development. PubMed · 1997 · 107 citations