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Sorafenib can cause delayed skin problems, so patients need careful monitoring.

The author now believes tricholemmal carcinoma is a rare type of infundibular squamous cell carcinoma and more research is needed on these tumors.

Cicatricial pattern hair loss is likely advanced common baldness, not a type of lichen planopilaris.

Drinking kava tea can cause a skin reaction with red, swollen bumps, which may improve with steroids.

The skin's dermal layer contains true stem cells with diverse functions and interactions that need more research to fully understand.

Early and aggressive treatment of scarring alopecia is important to prevent further hair follicle damage.

Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.

Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Polymeric nanoparticles show promise for treating skin diseases.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

Androgens can both increase and decrease hair growth in different parts of the body.

Certain mutations in a hair growth-related gene cause a type of genetic hair loss.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

EVAL membranes help create cell structures that can regrow hair follicles.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.