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research Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration

June 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Wnt ligand secretion by hair follicle cells is essential for hair growth and repair.

research Faculty Opinions Recommendation of FGF9 from Dermal γδ T Cells Induces Hair Follicle Neogenesis After Wounding

June 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

FGF9 from certain cells can trigger new hair growth during wound healing, but humans have fewer of these cells, which may limit hair regrowth.

research Faculty Opinions Recommendation of Promising Therapies for Treating and Preventing Androgenic Alopecia

December 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

There are several promising treatments for hair loss, including dutasteride, latanoprost, ketoconazole shampoo, anti-androgens, laser/light treatment, and platelet-rich plasma, but more research is needed.

research Faculty Opinions Recommendation of Thymic Peptides Differentially Modulate Human Hair Follicle Growth

October 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Thymic peptides can either promote or inhibit human hair growth.

research Faculty Opinions Recommendation of Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth

July 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Platelet-rich plasma can potentially increase hair growth and density, but more trials are needed to confirm its effectiveness and safety.

Faculty Opinions Recommendation of Hair Regrowth Following a Wnt- and Follistatin-Containing Treatment: Safety and Efficacy in a First-in-Man Phase 1 Clinical Trial

research Faculty Opinions Recommendation of Hair Regrowth Following a Wnt- and Follistatin-Containing Treatment: Safety and Efficacy in a First-in-Man Phase 1 Clinical Trial

July 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

New treatment with Wnt proteins and growth factors safely increases hair thickness.

research De Novo Production of Dermal Papilla Cells During the Anagen Phase of the Hair Cycle

December 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

New cells join the hair's dermal papilla during the growth phase, possibly affecting hair thickness.

research Faculty Opinions Recommendation of Loss of Desmocollin 3 in Mice Leads to Epidermal Blistering

September 2008 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Loss of Desmocollin 3 in mice causes skin blisters and hair loss.

research Faculty Opinions Recommendation of Targeted Skin Overexpression of the Mineralocorticoid Receptor in Mice Causes Epidermal Atrophy, Premature Skin Barrier Formation, Eye Abnormalities, and Alopecia

August 2007 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Overexpression of a specific receptor in mice skin causes skin thinning, early skin barrier formation, eye issues, and hair loss.

Faculty Opinions Recommendation of Effect of 1 mg/Day Finasteride on Concentrations of Serum Prostate-Specific Antigen in Men With Androgenic Alopecia: A Randomised Controlled Trial

research Faculty Opinions Recommendation of Effect of 1 mg/Day Finasteride on Concentrations of Serum Prostate-Specific Antigen in Men With Androgenic Alopecia: A Randomised Controlled Trial

February 2007 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Taking 1mg of finasteride daily for hair loss can lower PSA levels by 40-50%, so to keep PSA effective as a cancer screening tool, the PSA value should be doubled during treatment.

research Faculty Opinions Recommendation of Conditional Telomerase Induction Causes Proliferation of Hair Follicle Stem Cells

October 2005 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Activating telomerase can boost hair follicle stem cell growth and hair production.

research Faculty Opinions Recommendation of Efficacy and Safety of Topical Finasteride Spray Solution for Male Androgenetic Alopecia: A Phase III, Randomized, Controlled Clinical Trial

December 2022 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

research Faculty Opinions Recommendation of Bead-Jet Printing Enabled Sparse Mesenchymal Stem Cell Patterning Augments Skeletal Muscle and Hair Follicle Regeneration

December 2022 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

research Faculty Opinions Recommendation of There Is a Positive Dose-Dependent Association between Low-Dose Oral Minoxidil and Its Efficacy for Androgenetic Alopecia: Findings from a Systematic Review with Meta-Regression Analyses

October 2022 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

research Faculty Opinions Recommendation of Mesotherapy With Dutasteride for Androgenetic Alopecia: A Retrospective Study in Real Clinical Practice

August 2022 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

research Faculty Opinions Recommendation of Review of Oral Minoxidil as Treatment of Hair Disorders: In Search of the Perfect Dose

February 2022 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Low-dose oral minoxidil is a promising, safe treatment for various hair diseases, improving hair thickness and density, but more research is needed on long-term side effects and treatment duration.

research Faculty Opinions Recommendation of Topical Finasteride for the Treatment of Male Androgenetic Alopecia and Female Pattern Hair Loss: A Review of the Current Literature

December 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Topical finasteride is promising for hair loss with minimal side effects but needs more research and approval.

research Therapeutic Implications of Topical Cetirizine 1% in Treatment of Male Androgenetic Alopecia: A Case-Controlled Study

December 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

research Faculty Opinions Recommendation of Trichologic Response of Platelet-Rich Plasma in Androgenetic Alopecia Is Maintained During Combination Therapy

December 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

research Faculty Opinions Recommendation of Safety of Oral Bicalutamide in Female Pattern Hair Loss: A Retrospective Review of 316 Patients

September 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

research Faculty Opinions Recommendation of Sublingual Minoxidil for the Treatment of Male and Female Pattern Hair Loss: A Randomized, Double-Blind, Placebo-Controlled, Phase 1B Clinical Trial

September 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

research Faculty Opinions Recommendation of Safety of Low-Dose Oral Minoxidil for Hair Loss: A Multicenter Study of 1404 Patients

July 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

research Faculty Opinions Recommendation of Symmetry Breaking of Tissue Mechanics in Wound-Induced Hair Follicle Regeneration of Laboratory and Spiny Mice

June 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

research Faculty Opinions Recommendation of Post-Finasteride Syndrome: A Surmountable Challenge for Clinicians

May 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Clinicians need to better understand and treat Post-finasteride syndrome.

research Faculty Opinions Recommendation of Androgenetic Alopecia Present in the Majority of Hospitalized COVID-19 Patients – The 'Gabrin Sign'

June 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

research Faculty Opinions Recommendation of Female Pattern Hair Loss and Androgen Excess: A Report from the Multidisciplinary Androgen Excess and PCOS Committee

May 2019 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

research Faculty Opinions Recommendation of Inhibition of Beta-Catenin Signaling in Dermal Fibroblasts Enhances Hair Follicle Regeneration During Wound Healing

May 2019 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

research Faculty Opinions Recommendation of the Efficacy and Use of Finasteride in Women: A Systematic Review

January 2019 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

research Faculty Opinions Recommendation of Identification of Functional Patterns of Androgenetic Alopecia Using Transcriptome Profiling in Distinct Locations of Hair Follicles

April 2018 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Faculty Opinions Recommendation of Minoxidil Dose Response Study in Female Pattern Hair Loss Patients Determined to Be Non-Responders to 5% Topical Minoxidil

research Faculty Opinions Recommendation of Minoxidil Dose Response Study in Female Pattern Hair Loss Patients Determined to Be Non-Responders to 5% Topical Minoxidil

January 2017 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

60% of women who didn't respond to 5% minoxidil for hair loss showed significant improvement with a 15% minoxidil solution.

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