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Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Genetic screening is crucial for accurately diagnosing APS-1 due to its varied symptoms.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

AR polyglycine repeat doesn't cause baldness.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

Wnt, Eda, and Shh pathways are crucial for different stages of sweat gland development in mice.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

DHT, a testosterone byproduct, causes male pattern baldness.

Brg1 is crucial for hair growth and skin repair by maintaining stem cells and promoting regeneration.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

A gene called HDAC9 might be a new factor in male-pattern baldness.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Researchers created rat liver stem cells that could help repair liver failure in rats and may be useful for studying human liver diseases.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.

Hair follicles in people with alopecia have lower levels of a key blood vessel growth protein.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.

Disrupting Acvr1b in mice causes severe hair loss and thicker skin.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.