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Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.

Local testosterone treatment improved sexual desire in a female with fragile X syndrome.

Small hormonal imbalances can cause significant health problems, so more sensitive testing for hormone-disrupting chemicals is needed.

Hair follicles are important for drug delivery through the skin, but better methods are needed to understand and improve this process.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Thiocyanate helps hair growth and can be supplemented in diet or applied topically.

Genetic mutations can affect female sexual development, requiring personalized medical care.

Hormones affect skin aging, and treatments targeting hormonal balance may improve skin health.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Hair follicle biology advancements may lead to better hair growth disorder treatments.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Removing part of the vitamin D receptor stops vitamin D from working properly.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

CDP is crucial for lung and hair follicle cell development.

Latanoprost can make eyelashes longer, thicker, and darker.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.