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β-catenin is essential for stem cell activation and proliferation in hair follicles.

The research found that PCOS has common genetic factors regardless of how it is diagnosed and is linked to metabolic and reproductive issues.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

Growing human skin cells in a 3D environment can stimulate new hair growth.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

PCOS is caused by both genetics and environmental factors like diet and obesity.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Laser hair removal is the most requested cosmetic procedure and has become a scientifically-based treatment suitable for all skin types.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Special fiber materials boost the healing properties of certain stem cells.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.