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research Alopecia areata as an immune-related adverse event associated with response to immune checkpoint inhibitors
In this study, researchers using multistate modeling reported that patients with psoriasis treated with brodalumab had a higher probability of achieving and maintaining a therapeutic response compared to those treated with ustekinumab over 52 weeks, based on absolute PASI measurements.
research Extracellular vesicles from adipose-derived stem cells ameliorate ultraviolet B-induced skin photoaging by attenuating reactive oxygen species production and inflammation
This study found that adipose-derived stem cell extracellular vesicles reduced wrinkles and promoted cell proliferation in UVB-induced photoaging in mice by decreasing oxidative stress and inflammation.
research [Influence and mechanism of extracellular vesicles derived from human dermal papilla cells on skin fibrosis in mice].
In this study, human dermal papilla cell-derived extracellular vesicles (hDPC-EVs) were found to reduce skin fibrosis in mice by delivering miRNA-182-5p, which inhibits the TGF-β1 signaling pathway.
research Retinoids - new uses and new synthetic agents
New retinoids are effective for various skin conditions and are being developed to have fewer side effects.
research Pharmacokinetic and Therapeutic Dose Comparison of Diane-35 and IVF-C Inj 5000 IU in Common Quail
This study observed significant clinical effects, such as hair loss and testicular changes, in common quail treated with the steroids IVF-C Inj and Diane-35, especially highlighting cyproterone acetate's impact on vital organs like the liver.
research P97: Epidermal growth factor receptor inhibitor therapy induces a distinct inflammatory hair follicle response that includes a collapse of immune privilege
research Treatment of vitiligo with the topical Janus kinase inhibitor ruxolitinib: A 32-week open-label extension study with optional narrow-band ultraviolet B
research Quality of Life of Patients with Metastatic Breast Cancer Treated with Epirubicin and Docetaxel
This study found that the epirubicin-docetaxel chemotherapy regimen for metastatic breast cancer resulted in a clinical response in 55% of patients, with maintained global quality of life despite some impairments.
research Systemic corticosteroids in vitiligo: Evidence-based insights and practical considerations
This study reviewed evidence suggesting that systemic corticosteroids, particularly in pulse regimens like dexamethasone and betamethasone oral mini-pulse, effectively slow vitiligo progression and support repigmentation, while offering a favorable safety profile compared to continuous therapy.
research Evaluación pronóstica de la escala delta-sofa a los 3 y 5 días del ingreso en uci asociado al saps 3 y creación de un modelo objetivo para la adecuación ética del esfuerzo terapéutico
This study found that P144 (Disitertide) significantly reduced collagen deposition and improved muscle organization in a rabbit model of post-radiotherapy fibrosis, suggesting potential antifibrotic effects.
research 44047 Long Term Real-World Treat-to-Target Skin Clearance and Maintenance of Response with Risankizumab in Patients with Moderate to Severe Psoriasis From the CorEvitas Psoriasis Registry
Risankizumab effectively treats and maintains skin clearance in moderate-to-severe psoriasis.