Pharmacokinetic and Therapeutic Dose Comparison of Diane-35 and IVF-C Injection 5000 IU in Common Quail

    January 2025 in “ International Journal of Pharmacology ”
    Zain Ul Abideen, Mohsen A. Khormi, Sultan Areshi, Mehwish Raza, Muhammad Shahid Nadeem, Muhammad Amjad, Muhammad Saif Ullah, Aleem Ahmed Khan, Mukul Sharma, A. El‐Shabasy
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    TLDR Both steroids, especially cyproterone acetate, harm quail's vital organs.
    This study investigated the effects of two steroids, IVF-C Inj and Diane-35, on common quail, using 120 birds divided into winter and summer groups. The study found significant clinical symptoms such as hair loss, appetite loss, testicular enlargement, depression, and elevated body temperature in all treated birds. Histological analysis showed no significant changes in heart and skeletal muscle tissues, but liver failure and testicular darkening were associated with cyproterone acetate treatment. The study concludes that both steroids, particularly cyproterone acetate, have significant physiological effects on quail, emphasizing the need for caution due to negative impacts on vital organs.
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