Systemic Corticosteroids in Vitiligo: Evidence-Based Insights and Practical Considerations

Systemic corticosteroids are effective in managing vitiligo by halting disease progression and promoting partial repigmentation, particularly in rapidly progressive cases. This review highlights the efficacy and safety of pulse regimens like dexamethasone and betamethasone oral mini-pulse, which offer a better safety profile compared to continuous daily therapy. The study emphasizes the importance of careful patient selection, appropriate dosing, and regular monitoring to optimize outcomes and minimize adverse effects. Systemic corticosteroids are a key component in vitiligo treatment, often used alongside other therapies for best results.