30 citations
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July 2007 in “PubMed” This study found that oral mini-pulse therapy with betamethasone was safe and effective for treating extensive alopecia areata in a majority of patients.
16 citations
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March 1996 in “PubMed” In this study, an 8-year-old girl with alopecia totalis experienced complete hair regrowth on the OMP regime after incomplete results with a previous treatment of oral betamethasone.
4 citations
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January 2019 in “Open Access Macedonian Journal of Medical Sciences” In this study, oral mini-pulse methylprednisolone therapy for alopecia areata was reported to be effective and safe over 6 months, with 82.2% of patients recovering well and no adverse events observed.
January 2021 in “International journal of basic and clinical pharmacology” This study found that hydroxychloroquine was less effective than betamethasone oral mini pulse therapy in managing alopecia areata, with patients on hydroxychloroquine experiencing score increases and more relapses at 24 weeks, though adverse event rates were similar between the groups.
November 2025 in “Journal of Dermatological Treatment” This study reviewed a corticosteroid treatment regimen for a 52-year-old woman with extensive alopecia areata, showing significant hair regrowth and sustained remission over 12 months, suggesting oral mini-pulse therapy as a viable alternative for those ineligible for JAK inhibitors.
