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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The Rotterdam Study aims to understand various diseases in older adults.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Targeted cancer therapies often cause serious skin problems that need careful management.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.

Female Pattern Hair Loss affects women's self-esteem and needs more research for better treatment.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

The representation of skin conditions in medical reviews partly matches their real-world impact.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

No cure for female pattern hair loss, but various effective treatments exist.

Scalp cooling can reduce chemotherapy-induced hair loss and should be available in all hospitals.

Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Psoriasis is linked to other autoimmune diseases and involves a specific inflammatory process.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

Birth control pills increase the risk of blood clots, especially within the first year and with certain types.

Targeted cancer therapies have a significant but lower risk of causing hair loss compared to chemotherapy.

FAGA diagnosis uses blood tests and trichoscopy, with treatments like topical minoxidil, oral anti-androgens, and hormone-modulating drugs.

The article suggests using four questions to tell apart necessary medicalization from excessive medicalization, focusing on problem significance, social expectations, medical understanding, and effective resolution.