Follow-Up of 1 mg Finasteride Treatment of Male Pattern Baldness: Difference Between Clinical Trials and Private Office Follow-Up

    May 2004 in “ Dermatologic Surgery
    Marvin J. Rapaport
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    TLDR Most men stopped using finasteride for baldness due to unsatisfactory results or were lost to follow-up, and those who continued saw minimal to moderate improvement.
    In a retrospective study from 2004, 1,261 men were prescribed 1 mg finasteride for male pattern baldness and followed up via phone calls every 3 months. After 1 to 3 years, only 32% (414 men) continued with the treatment, 24% (297 men) stopped due to unsatisfactory results, and 44% (549 men) were lost to follow-up. Of the men who continued, 211 returned detailed questionnaires, with only a small percentage reporting hair growth. The study aimed to inform future prescribing practices and set realistic expectations for finasteride, underscoring the necessity for independent studies to assess long-term outcomes. The findings suggested that patients perceived the drug's benefits as minimal to moderate, and the study highlighted the need for objective measures in clinical trials to prevent bias in prescribing decisions.
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      by nkrata in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

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      in Is this regrowth?  58 upvotes 6 months ago
      The user has been using Minoxidil, vitamins, and a derma roller for 2.5 months with some regrowth observed. They are hesitant to add finasteride or dutasteride due to potential side effects, considering topical finasteride as a safer option.

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      in Finasteride/Dutasteride  332 upvotes 2 years ago
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