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    Glossary Estrogen Signaling

    hormone estrogen communicates with cells to regulate functions

    Estrogen signaling refers to the process by which the hormone estrogen communicates with cells to regulate various biological functions. This involves estrogen binding to its receptors, which can be located on the cell surface or within the cell, leading to changes in gene expression and cellular activity. This signaling pathway is crucial for reproductive health, bone density, and even hair growth, and disruptions in estrogen signaling can contribute to conditions like alopecia and osteoporosis.

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    1. Estrogen and androgen signaling in the pathogenesis of BPH Nature reviews. Urology · 2011 · 149 citations
    2. Role of estrogen receptor signaling in the control of the hair follicle cycle 2004
    3. Hair Cycle Control by Estrogens: Catagen Induction via Estrogen Receptor (ER)-α Is Checked by ERβ Signaling Endocrinology · 2005 · 92 citations
    4. The Hair Follicle as an Estrogen Target and Source Endocrine Reviews · 2006 · 159 citations
    5. Specific morphogenetic events in mouse external genitalia sex differentiation are responsive/dependent upon androgens and/or estrogens Differentiation · 2012 · 51 citations
    6. Estrogens and the hair follicle. Ostrogene und der Haarfollikel Journal der Deutschen Dermatologischen Gesellschaft · 2004 · 50 citations
    7. Estrogen modulates mesenchymal-epidermal interactions in the adult nipple Development · 2017 · 4 citations
    8. The GPR30 agonist G-1 promotes hair growth via Wnt/Hedgehog signaling in mice Frontiers in Pharmacology · 2025
    9. Signaling Involved in Hair Follicle Morphogenesis and Development International Journal of Molecular Sciences · 2014 · 223 citations
    10. Epidermal Wnt/beta-catenin signalling promotes dermal adipocyte differentiation during hair follicle morphogenesis and regeneration Journal of Dermatological Science · 2012
    11. On the Effect of Estrogen Receptor Agonists and Antagonists on the Mouse Hair Follicle Cycle Journal of Investigative Dermatology · 1998 · 11 citations
    12. Large Scale Gene Expression Profiles of Regenerating Inner Ear Sensory Epithelia PLoS ONE · 2007 · 77 citations
    13. Hormonal regulation in male androgenetic alopecia—Sex hormones and beyond: Evidence from recent genetic studies Experimental Dermatology · 2020 · 15 citations
    14. 25 years of ERβ: a personal journey Journal of molecular endocrinology · 2021 · 11 citations
    15. Blackcurrant Extract with Phytoestrogen Activity Alleviates Hair Loss in Ovariectomized Rats Molecules · 2019 · 9 citations
    16. TMT-based quantitative proteomics reveals the genetic mechanisms of secondary hair follicle development in fine-wool sheep PLoS ONE · 2025 · 2 citations
    17. Transcriptome sequencing reveals the expression profiles of lncRNAs and mRNAs in goat skin tissues with different types of wool coats Scientific Reports · 2025 · 1 citations
    18. Transcriptome sequencing reveals the key genes associated with hair follicle development in Qianhua Mutton Merino Frontiers in Veterinary Science · 2025
    19. Baicalin Against Androgenetic Alopecia: A Network Pharmacology Study 2025
    20. Diffuser Haarausfall und klinische Endokrinologie: Neue Erkenntnisse Journal für Kardiologie (Krause & Pachernegg GmbH) · 2013
    21. Integrating proteomics revealed the key targets for molecular breeding of fine cashmere traits in cashmere goats Frontiers in Veterinary Science · 2025
    22. Transcriptome sequencing reveals the expression profiles of lncRNAs and mRNAs in goat skin tissues with different types of wool coats 2025
    23. LncRNAs regulate the cyclic growth and development of hair follicles in Dorper sheep Frontiers in veterinary science · 2023
    24. Anogenital distance as a biomarker for incomplete masculinization : Molecular mechanisms in the perineum Research Portal Denmark · 2020
    25. Hair Sciences: An interview with Dr. Rodney Sinclair on female pattern hair loss Hair transplant forum international · 2009
    26. Clinical-exome sequencing unveils the genetic landscape of polycystic ovarian syndrome (PCOS) focusing on lean and obese phenotypes: implications for cost-effective diagnosis and personalized treatment Scientific Reports · 2024 · 13 citations
    27. Oestrogen functions in skin and skin appendages Expert Opinion on Therapeutic Targets · 2005 · 68 citations
    28. Thyrotropin-releasing hormone and oestrogen differentially regulate prolactin and prolactin receptor expression in female human skin and hair follicles <i>in vitro</i> British Journal of Dermatology · 2010 · 37 citations
    29. Adrenal Cortex Tumors and Hyperplasias InTech eBooks · 2011 · 2 citations
    30. Genetic Differences between Male and Female Pattern Hair Loss in a Korean Population Life · 2024