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Transgender females can reach their target estrogen levels using estradiol patches, especially if oral treatments fail or if they're at risk for blood clots. Often, the highest dose patch is needed.

Estrogen-progestin contraception lowers ovarian, endometrial, and colon cancer risk but may raise breast and cervical cancer risk, helps with menstrual and acne issues, and new methods are as effective as pills. Metformin helps overweight women with PCOS and insulin resistance, and dopamine agonists treat prolactinomas.

Higher androgen receptor levels in bald areas may cause hair loss, while estrogen receptors have less impact.

Treatments for hair loss include estrogen therapy and special shampoos.

Genetics, low estrogen, and low iron levels contribute to female hair loss, with specific scalp signs indicating severity.

Adding estrogen increased bone mass in a transsexual man undergoing hormone therapy.

Birth control pills with low-dose estrogen and antiandrogenic progestins can effectively treat acne.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Older women often have vulva issues due to less estrogen, which can be misdiagnosed and lead to wrong treatments.

Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.

A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.

Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Human sebaceous glands can grow normally for a week without certain growth factors, and adding estrogen reduces their oil production without affecting cell growth.

The medication combination did not affect glucose tolerance but increased some cholesterol levels due to its estrogen component.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Sex hormones, especially androgens, play a key role in causing acne.

Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.