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Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Nanotechnology improves hair care products by enhancing ingredient stability, targeting treatment, and reducing side effects, but more research on its toxicity is needed.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

Distinct β-catenin patterns are linked to cell growth, not cell death, in lung cancer.

Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.

Some alternative treatments for hair loss might work, but more research is needed.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Different types of hair loss in lupus need careful diagnosis for proper treatment.

Understanding how EDC genes are regulated can help develop better drugs for skin diseases.

Cyclophosphamide has serious side effects, but long-term follow-up can help manage risks.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Scalp cooling can help prevent chemotherapy-induced hair loss with a 50-90% success rate and is safe for patients.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

NSAIDs may not affect soft tissue healing but should be used carefully for bone fractures and more research is needed to understand sex differences in response.

Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Autoimmune diseases can cause hair loss, and early treatment is important to prevent permanent damage.

The document concludes that there are various treatments for different types of alopecia, but more research is needed for evidence-based treatments.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.

Applying calreticulin can speed up wound healing in diabetics.

Minoxidil helps treat eyebrow thinning, monilethrix, early hair loss, and shortens chemo-related hair loss.

Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.

The document concludes that inherited epidermolysis bullosa is a challenging genetic condition requiring multidisciplinary care and new treatments.

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

Skin organoids are a promising new model for studying human skin development and testing treatments.