1 citations
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January 2004 in “The Internet Journal of Geriatrics and Gerontology” This review discusses the clinical aspects, diagnosis, and treatment options for androgenetic alopecia, ultimately calling for further research, particularly regarding older populations and possible health risks.
Trichodysplasia spinulosa can occur after a heart transplant due to immunosuppressive drugs.
7 citations
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January 2020 in “Journal of Dermatology” This study described specific skin and hair follicle abnormalities in three Japanese patients with Cantu syndrome, which may relate to the regulation role of SUR2 in hair follicle growth.
9 citations
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February 2007 in “JAMA” PCOS is a common inherited condition causing cysts, irregular periods, and increased diabetes risk in women.
January 2022 in “Function” This article analyzes the potential for insights from monogenic disorders to inform the understanding and treatment of common polygenic diseases, though complete predictability based on genotype remains unrealistic.
1 citations
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December 2016 This computational study developed a regulatory model linking key genes and miRNAs to cardiac senescence, validated by connecting 94% of these elements to existing cardiac aging research.
April 2016 in “Journal of Urology and Nephrology Open Access” This abstract discusses treatment options for benign prostatic hyperplasia and provides no new clinical results.
February 2024 in “European heart journal. Case reports” This case report highlights the need for a multidisciplinary approach in managing complex cardio-obstetric patients, as demonstrated by a pregnant woman with a large pericardial effusion successfully treated with a surgical pericardial window.
26 citations
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January 2000 in “Hormone research in paediatrics” This review discusses the relationship between hyperandrogenism and insulin resistance in PCOS, focusing on insulin dynamics, molecular mechanisms, genetic studies, and potential long-term treatments, but presents no new clinical results.
69 citations
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November 2010 in “Middle East Fertility Society Journal” This review discusses the multifactorial origins and pathophysiology of PCOS and highlights the effectiveness of lifestyle modifications as a first-line intervention, reporting no new research results.
16 citations
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September 2018 in “Clinical Biochemistry” This paper discusses the link between polycystic ovarian syndrome (PCOS) and health issues like infertility and cardiovascular diseases, caused by both genetic and environmental factors, but reports no new clinical findings.
January 2020 in “Asian Journal of Basic Science & Research” This review discusses the role of Nutrease powder in managing hormonal disturbances in polycystic ovary syndrome and reports no new clinical results.
1533 citations
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October 2008 in “Endocrine reviews” This research highlights that engineered mice lacking the vitamin D receptor show multiple health issues similar to human vitamin D deficiency, underscoring the widespread impacts of the vitamin D endocrine system.
117 citations
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May 2017 in “Human Reproduction Update” This review examines the epidemiology, pathophysiology, diagnosis, and management strategies for non-classic congenital hyperplasia due to 21-hydroxylase deficiency, and provides evidence-based recommendations for its treatment and genetic counseling.
75 citations
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January 2014 in “Korean Journal of Urology” This review discusses the adverse effects of 5α-reductase inhibitors, finasteride and dutasteride, on sexual, psychological, and vascular health, emphasizing the need for physicians to inform patients of these risks.
75 citations
,
June 1999 in “Pediatric Clinics of North America” This review discusses the clinical features and therapeutic goals for teenagers with PCOS, emphasizing the need for further research into its causes and potential long-term health risks, but reports no new clinical results.
18 citations
,
June 1998 in “Circulation” This letter discusses how outdated measurement technology may obscure evidence of essential fatty acid deficiency in low-fat diet patients, potentially leading to undiagnosed EFA insufficiencies related to heart disease.
7 citations
,
February 2019 in “International Journal of Dermatology” This review discusses factors influencing hair pigmentation and the etiology of canities, noting the lack of clarity in underlying mechanisms and calling for further research on treatment options.
1 citations
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February 1954 in “Journal of the American Geriatrics Society” Steroid hormones can help treat aging issues and improve health in elderly people.
February 2025 in “International Journal of Pharmaceutical Research and Applications” This article reviews the symptoms, diagnosis, and management of polycystic ovary syndrome, emphasizing lifestyle changes and medical interventions, but presents no new findings.
July 2015 in “Cambridge University Press eBooks” The document concludes that careful history and physical exams are crucial for accurately diagnosing polycystic ovary syndrome and distinguishing it from other similar conditions.
418 citations
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June 2003 in “Endocrine Reviews” This review discusses the relationship between polycystic ovary syndrome and cardiovascular risk, noting a possible adverse impact on risk profiles and subclinical atherosclerosis but no clear increase in premenopausal cardiovascular events; it presents no new clinical results.
6 citations
,
April 2019 in “Endocrinology and Metabolism Clinics of North America” This study observed that testosterone therapy in transgender men enhances both physical and mental health, is safe in the short and middle term with proper follow-up, and highlights the need for endocrinologists to provide gender-affirming care despite its limited presence in medical education.
9 citations
,
July 2007 in “Circulation Research” This study found that disruptions in planar cell polarity signaling are implicated in congenital heart defects and cardiomyopathy in developing mouse hearts, associated with early cardiomyocyte disorganization and improper heart looping.
44 citations
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March 2015 in “PLOS ONE” This study found that FGF-9 treatment in diabetic mice improved heart function after myocardial infarction by decreasing monocyte infiltration and promoting anti-inflammatory macrophage differentiation.
16 citations
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September 2019 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that the retinol dehydrogenases SDR16C5 and SDR16C6 in mice play a crucial role in skin retinol dehydrogenase activity, affecting hair growth and gland functions without impacting survival.
22 citations
,
October 2004 in “Journal of Investigative Dermatology” This study identified the rough coat mutation in mice, but found that LOXL is not the causal gene, although its downregulation might contribute to related phenotypic changes.
17 citations
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November 2015 in “Oxidative Medicine and Cellular Longevity” This study suggests that FGF-9 treatment may improve cardiac function by reducing vascular apoptosis and enhancing angiogenesis in infarcted hearts of both nondiabetic and diabetic mice.
December 2021 in “Indian Journal of Dermatology, Venereology and Leprology” In this study, androgenetic alopecia patients exhibited more nailfold capillary abnormalities, suggesting a potential link between microcirculation issues and the condition.
1 citations
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October 2025 in “Frontiers in Cardiovascular Medicine” This review examines AAS-related deaths and finds that anabolic-androgenic steroid abuse may lead to severe cardiac abnormalities, contributing to fatal arrhythmias and sudden cardiac death in young athletes and bodybuilders.