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    Glossary Endothelial Function

    cells lining blood vessels regulate blood flow and pressure

    Endothelial function refers to how well the endothelium, the thin layer of cells lining the blood vessels, works. It plays a crucial role in regulating blood flow, blood pressure, and the formation of new blood vessels. Healthy endothelial function is essential for cardiovascular health, while dysfunction can lead to conditions like atherosclerosis and hypertension.

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    Research 30 of 1000+

    1. Improvement of endothelial function with metformin and rosiglitazone treatment in women with polycystic ovary syndrome European journal of endocrinology · 2008 · 56 citations
    2. Influence of spironolactone treatment on endothelial function in non-obese women with polycystic ovary syndrome European Journal of Endocrinology · 2011 · 50 citations
    3. The evaluation of endothelial function with flow-mediated dilatation and carotid intima media thickness in young nonobese polycystic ovary syndrom patients; existence of insulin resistance alone may not represent an adequate condition for deterioration of endothelial function Fertility and Sterility · 2008 · 44 citations
    4. 15-Hydroxyprostaglandin Dehydrogenase Inhibitor Restores Endothelial Function Under Dihydrotestosterone-Induced Stress in Human Dermal Microvascular Endothelial Cells Molecules · 2025
    5. Peroxisome proliferator-activated receptors-mediated diabetic wound healing regulates endothelial cells’ mitochondrial function via sonic hedgehog signaling Burns & Trauma · 2025 · 5 citations
    6. Disfunción eréctil : función endotelial e interacción hormonal, efectos sobre la salud vascular -De la fisiopatología molecular a los aspectos clínicos- Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya) · 2025
    7. Loss‐of‐function of Endothelin receptor type A results in Oro‐Oto‐Cardiac syndrome American Journal of Medical Genetics Part A · 2020 · 11 citations
    8. Interleukin-25-Mediated-IL-17RB Upregulation Promotes Cutaneous Wound Healing in Diabetic Mice by Improving Endothelial Cell Functions Frontiers in Immunology · 2022 · 34 citations
    9. Effect of Diurnal Blood Pressure on Endothelial Functions in Essential Hypertensive Patients Journal of the American College of Cardiology · 2013
    10. Fibrous scaffolds potentiate the paracrine function of mesenchymal stem cells: A new dimension in cell-material interaction Biomaterials · 2017 · 182 citations
    11. Dual-functional hybrid quaternized chitosan/Mg/alginate dressing with antibacterial and angiogenic potential for diabetic wound healing Journal of Orthopaedic Translation · 2021 · 43 citations
    12. RGDSP-functionalized peptide hydrogel stimulates growth factor secretion via integrin αv/PI3K/AKT axis for improved wound healing by human amniotic mesenchymal stem cells Frontiers in Bioengineering and Biotechnology · 2024 · 6 citations
    13. Mandibulofacial dysostosis with alopecia results from ETAR gain-of-function mutations via allosteric effects on ligand binding Journal of Clinical Investigation · 2023 · 4 citations
    14. Alk1 acts in non-endothelial VE-cadherin+ perineurial cells to maintain nerve branching during hair homeostasis Nature communications · 2023
    15. Serum vascular endothelial growth factor B is elevated in women with polycystic ovary syndrome and can be decreased with metformin treatment Clinical Endocrinology · 2015 · 18 citations
    16. Single-cell analysis reveals distinct functional heterogeneity of CD34+ cells in anagen wound and diabetic wound Biochemical and Biophysical Research Communications · 2022 · 7 citations
    17. Extracellular vesicles from 3D cultured dermal papilla cells improve wound healing via Krüppel-like factor 4/vascular endothelial growth factor A -driven angiogenesis Burns and trauma · 2023 · 1 citations
    18. Strawberry guava extract promotes hair growth by enhancing skin blood flow and vascular endothelial growth factor production Functional Foods in Health and Disease · 2026
    19. Dual growth factor releasing multi-functional nanofibers for wound healing Acta Biomaterialia · 2013 · 355 citations
    20. LL-37 stimulates the functions of adipose-derived stromal/stem cells via early growth response 1 and the MAPK pathway Stem cell research & therapy · 2016 · 53 citations
    21. A regenerative stem cell-derived matrix accelerates functional dermal wound repair in a preclinical diabetic model 2026
    22. Influence of Surface Functional Groups on the Hair Growth-Promoting Activities of Nanochitins: An In Vitro Analysis Biomacromolecules · 2025
    23. Long-term Oral Administration of 5α-reductase Inhibitor Attenuates Erectile Function by Inhibiting Autophagy and Promoting Apoptosis of Smooth Muscle Cells in Corpus Cavernosum of Aged Rats Urology · 2013 · 34 citations
    24. Sustained Postnatal Skin Regeneration Upon Prenatal Application of Functionalized Collagen Scaffolds Tissue Engineering Part A · 2019 · 8 citations
    25. Biphasic Regulation of HMG-CoA Reductase Expression and Activity during Wound Healing and Its Functional Role in the Control of Keratinocyte Angiogenic and Proliferative Responses Journal of Biological Chemistry · 2008 · 27 citations
    26. Metformin: an old medication of new fashion: evolving new molecular mechanisms and clinical implications in polycystic ovary syndrome European journal of endocrinology · 2009 · 200 citations
    27. Pathophysiology of the Behçet's Disease Pathology Research International · 2011 · 34 citations
    28. From Primary MSC Culture of Adipose Tissue to Immortalized Cell Line Producing Cytokines for Potential Use in Regenerative Medicine Therapy or Immunotherapy International Journal of Molecular Sciences · 2021 · 13 citations
    29. Metformin effects on Polycystic Ovarian Syndrome East African scholars journal of medical sciences · 2023
    30. PD49-03 IS TADALAFIL ASSOCIATED WITH DECREASED RISK OF MAJOR ADVERSE CARDIAC EVENTS OR VENOUS THROMBOEMBOLISM IN MEN WITH LOWER URINARY TRACT SYMPTOMS? 2022